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Zap-X Radiosurgery System: Initial Clinical Experience in a Recurrent Gamma Knife Case Series.
Cureus
November 2024
Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, JPN.
Introduction: The ZAP-X® Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) is expected to be a highly accurate next-generation treatment system that enables gyro-stereotactic irradiation of intracranial lesions. In this study, we report the initial treatment course using ZAP-X for intracranial lesions that recurred after Gamma Knife (GK) treatment.
View Article and Find Full Text PDFNavigating Extrapulmonary Tuberculosis: A Case Series from a Tertiary Care Facility Highlighting Rare Presentations, Diagnostic Challenges, Drug Resistance, and Therapeutic Complexities.
Int J Mycobacteriol
October 2024
Department of Pulmonary Medicine, Medical College, Baroda and SSGH, Vadodara, Gujarat, India.
Background: Extrapulmonary tuberculosis (EP-TB) constitutes one-fifth of all tuberculosis (TB) cases. EP-TB mimics common infections which pose diagnostic dilemma, requires extensive diagnostics that culminate into therapeutic delay often resulting in irrational and empirical institution of antitubercular therapy (ATT) in challenging cases. This supplemented by poor treatment compliance resulted in emergence of Drug-resistant (DR) strains of EP-TB which further impedes the path to recovery.
View Article and Find Full Text PDFEfficacy and Safety Evaluation of Immune Checkpoint Inhibitors in Combination With Chemotherapy for Extensive Small Cell Lung Cancer: Real-World Evidence.
Cancer Med
December 2024
Department of Thoracic Oncology, Kansai Medical University Hospital, Osaka, Japan.
Introduction: Extensive small cell lung cancer (ES-SCLC) are currently managed using first-line chemotherapy options, including atezolizumab (Atezo) plus etoposide and carboplatin (CE) or durvalumab (Durva) plus etoposide with either cisplatin (PE) or carboplatin (CE). However, a definitive distinction in therapeutic effects between Atezo and Durva in these regimens remains unestablished.
Methods: We analyzed data from 100 patients diagnosed with ES-SCLC who received immune checkpoint inhibitors (ICIs) as first-line chemotherapy.
Intracerebral Solitary Fibrous Tumor in Collision With Metastatic Colonic Adenocarcinoma.
Cureus
November 2024
Neurosurgery, Novant Health Presbyterian Medical Center, Charlotte, USA.
A collision tumor is a rare neoplastic lesion consisting of two or more coexisting, distinct cell line entities. In this report, we present the case of a 56-year-old male patient with a history of colon cancer who presented to the emergency room with visual deficits that had started about eight months earlier. An ophthalmologic examination reported left homonymous hemianopsia, prompting a brain MRI, which showed a right posterior temporal extra-axial mass concerning intracerebral metastatic colon cancer, in consideration of patient history.
View Article and Find Full Text PDFA rare case of dedifferentiated intracranial solitary fibrous tumor with chondrosarcomatous differentiation.
Neuropathology
December 2024
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
This report details a rare case of a 30-year-old female presenting with neurological symptoms, including headaches, seizures, and left-sided weakness. Imaging revealed a mass in the right parafalcine region of her brain. Surgical resection identified a tumor with two distinct components.
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