AI Article Synopsis
- Advances in technology have accelerated research on the immune responses triggered by SARS-CoV-2, the virus behind COVID-19.
- The article highlights modern techniques used to analyze B cell responses to the virus.
- Understanding these immune responses is crucial for public health strategies during the pandemic.
Article Abstract
Critical technological advances have enabled the rapid investigations into the immune responses elicited by SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. In this Comment, we discuss the cutting-edge methods used to deconvolute the B cell responses against this virus, and the significant impact they have had in the ongoing public health crisis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703369 | PMC |
| http://dx.doi.org/10.1038/s41592-022-01450-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Targeted FTO knockout in endothelial cells Boosts adhesion and lowers inflammatory infiltration to alleviate pulmonary arterial hypertension.
Biochem Biophys Res Commun
January 2025
Department of Ultrasonography, Fuwai Yunnan Hospital, Chinese Academy of Medical, Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, 650102, China. Electronic address:
Pulmonary arterial hypertension (PAH) is a syndrome characterized by increased pulmonary vascular resistance and elevated pulmonary artery pressure, ultimately leading to right heart failure and even death. Increasing evidence implicates the fat mass and obesity-associated protein (FTO) in various metabolic and inflammatory pathways; however, its role in pulmonary endothelial function and PAH remains largely unexplored. In this study, we examined the effects of endothelial cell-specific FTO knockout on PAH development.
View Article and Find Full Text PDFEnvironmental variability across space and time drives the recolonization pattern of a historically persecuted large carnivore.
Proc Natl Acad Sci U S A
February 2025
Faculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences, Ås 1432, Norway.
Wildlife populations are not static. Intrinsic and extrinsic factors affect individuals, which lead to spatiotemporal variation in population density and range. Yet, dynamics in density and their drivers are rarely documented, due in part to the inherent difficulty of studying long-term population-level phenomena at ecologically meaningful scales.
View Article and Find Full Text PDFStatoliths function in gravity perception in plants: yes, no, yes!
Planta
January 2025
Department of Biomedical Engineering and Science, Florida Institute of Technology, Melbourne, FL, 32901, USA.
The starch-statolith theory was established science for a century when the existence of gravitropic, starchless mutants questioned its premise. However, detailed kinetic studies support a statolith-based mechanism for graviperception. Gravitropism is the directed growth of plants in response to gravity, and the starch-statolith hypothesis has had a consensus among scientists as the accepted model for gravity perception.
View Article and Find Full Text PDFSevere bradycardia in patients with obstructive sleep apnoea and good early response to CPAP.
Sleep Breath
January 2025
Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland.
Background: Obstructive sleep apnoea (OSA) may lead to heart rhythm abnormalities including bradycardia. Our aim was to ascertain clinical and echocardiographic parameters in patients with OSA in whom severe bradycardia was detected in an outpatient setting, as well as to evaluate the efficacy of CPAP therapy on heart rate normalization at the early stages of treatment.
Methods: Fifteen patients mild, moderate or severe OSA and concomitant bradycardia were enrolled.
Piezo-Capacitive Flexible Pressure Sensor with Magnetically Self-Assembled Microneedle Array.
ACS Sens
January 2025
CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, P. R. China.
Flexible pressure sensors are pivotal in advancing artificial intelligence, the Internet of Things (IoT), and wearable technologies. While microstructuring the functional layer of these sensors effectively enhances their performance, current fabrication methods often require complex equipment and time-consuming processes. Herein, we present a novel magnetization-induced self-assembly method to develop a magnetically grown microneedle array as a dielectric layer for flexible capacitive pressure sensors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!