Terrestrial evaporation (E) is a key climatic variable that is controlled by a plethora of environmental factors. The constraints that modulate the evaporation from plant leaves (or transpiration, E) are particularly complex, yet are often assumed to interact linearly in global models due to our limited knowledge based on local studies. Here, we train deep learning algorithms using eddy covariance and sap flow data together with satellite observations, aiming to model transpiration stress (S), i.e., the reduction of E from its theoretical maximum. Then, we embed the new S formulation within a process-based model of E to yield a global hybrid E model. In this hybrid model, the S formulation is bidirectionally coupled to the host model at daily timescales. Comparisons against in situ data and satellite-based proxies demonstrate an enhanced ability to estimate S and E globally. The proposed framework may be extended to improve the estimation of E in Earth System Models and enhance our understanding of this crucial climatic variable.
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http://dx.doi.org/10.1038/s41467-022-29543-7 | DOI Listing |
JAMA Netw Open
January 2025
Medical Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Importance: Evolving breast cancer treatments have led to improved outcomes but carry a substantial financial burden. The association of treatment costs with the cost-effectiveness of screening mammography is unknown.
Objective: To determine the cost-effectiveness of population-based breast cancer screening in the context of current treatment standards.
Psychol Serv
January 2025
Center for Health Equity Research and Promotion, Department of Veterans Affairs Pittsburgh Healthcare System.
Chronic insomnia is one of the most common health problems among veterans and can significantly impact health, function, and quality of life. Brief behavioral treatment for insomnia (BBTI), an adaptation of cognitive behavioral therapy for insomnia (CBT-I), was developed to help increase access to care outside of specialty settings. However, training providers alone is rarely sufficient, and implementation strategies are needed for successful uptake, adoption, and sustainable delivery of care.
View Article and Find Full Text PDFAm J Manag Care
December 2024
GRAIL, Inc., 1525 O'Brien Dr, Menlo Park, CA 94025. Email:
Objectives: Multicancer early detection (MCED) testing could result in earlier cancer diagnosis, thereby improving survival and reducing treatment costs. This study evaluated the cost-effectiveness of MCED testing plus usual care (UC) screening while accounting for the impact of clinical uncertainty and population heterogeneity for an MCED test with broad coverage of solid cancer incidence.
Study Design: Cost-effectiveness analysis of MCED testing plus UC vs UC alone in an adult population in the US.
Introduction: Endoscopic ablation is the mainstay treatment for dysplastic Barrett's esophagus (BE), of which radiofrequency ablation (RFA) and argon plasma coagulation (APC) are the most widely available options.
Objectives: We aimed to analyze the safety and outcomes of endoscopic ablation for BE within Polish centers.
Patients And Methods: We retrospectively analyzed data from three high-volume endoscopy units between 2002-2024.
Front Mol Biosci
December 2024
Department of Teacher Education, NLA University College, Oslo, Norway.
Background: Breast cancer (BC) is a significant cause of morbidity and mortality in women. Although the important role of metabolism in the molecular pathogenesis of BC is known, there is still a need for robust metabolomic biomarkers and predictive models that will enable the detection and prognosis of BC. This study aims to identify targeted metabolomic biomarker candidates based on explainable artificial intelligence (XAI) for the specific detection of BC.
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