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HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis.
Front Biosci (Landmark Ed)
January 2025
The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Health Science Center, 410013 Changsha, Hunan, China.
Background: α thalassemia/mental retardation syndrome X-linked (ATRX) serves as a part of the sucrose nonfermenting 2 (SNF2) chromatin-remodeling complex. In interphase, ATRX localizes to pericentromeric heterochromatin, contributing to DNA double-strand break repair, DNA replication, and telomere maintenance. During mitosis, most ATRX proteins are removed from chromosomal arms, leaving a pool near the centromere region in mammalian cells, which is critical for accurate chromosome congression and sister chromatid cohesion protection.
View Article and Find Full Text PDFEvolutionary Trajectories of Shoots vs. Roots: Plant Volatile Metabolomes Are Richer but Less Structurally Diverse Belowground in the Tropical Tree Genus .
Plants (Basel)
January 2025
Department of Biological Sciences, Binghamton University, Binghamton, NY 13902, USA.
The breadth and depth of plant leaf metabolomes have been implicated in key interactions with plant enemies aboveground. In particular, divergence in plant species chemical composition-amongst neighbors, relatives, or both-is often suggested as a means of escape from insect herbivore enemies. Plants also experience strong pressure from enemies such as belowground pathogens; however, little work has been carried out to examine the evolutionary trajectories of species' specialized chemistries in both roots and leaves.
View Article and Find Full Text PDFZero-Shot Traffic Identification with Attribute and Graph-Based Representations for Edge Computing.
Sensors (Basel)
January 2025
School of Economics and Management, Beijing Information Science & Technology University, Beijing 100192, China.
With the proliferation of mobile terminals and the rapid growth of network applications, fine-grained traffic identification has become increasingly challenging. Methods based on machine learning and deep learning have achieved remarkable results, but they heavily rely on the distribution of training data, which makes them ineffective in handling unseen samples. In this paper, we propose AG-ZSL, a zero-shot learning framework based on traffic behavior and attribute representations for general encrypted traffic classification.
View Article and Find Full Text PDFComparison of Manual, Automatic, and Voice Control in Wheelchair Navigation Simulation in Virtual Environments: Performance Evaluation of User and Motion Sickness.
Sensors (Basel)
January 2025
Instituto de Ciencias Aplicadas y Tecnología (ICAT), Universidad Nacional Autónoma de México, Ciudad de México C.P. 04510, Mexico.
Mobility is essential for individuals with physical disabilities, and wheelchairs significantly enhance their quality of life. Recent advancements focus on developing sophisticated control systems for effective and efficient interaction. This study evaluates the usability and performance of three wheelchair control modes manual, automatic, and voice controlled using a virtual reality (VR) simulation tool.
View Article and Find Full Text PDFAngle-Dependent Adhesive Mechanics in Hard-Soft Cylindrical Material Interfaces.
Materials (Basel)
January 2025
Department of System Dynamics and Friction Physics, Institute of Mechanics, Technische Universität Berlin, 10623 Berlin, Germany.
In this research, the adhesive contact between a hard steel and a soft elastomer cylinder was experimentally studied. In the experiment, the hard cylinder was indented into the soft one, after which the two cylinders were separated. The contact area between the cylinders was elliptical in shape, and the eccentricity of this increased as the angle between the axes of the contacting cylinders decreased.
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