Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks.
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http://dx.doi.org/10.1073/pnas.2113561119 | DOI Listing |
Sci Total Environ
January 2025
Department of Civil and Systems Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
The COVID-19 pandemic highlighted shortcomings in forecasting models, such as unreliable inputs/outputs and poor performance at critical points. As COVID-19 remains a threat, it is imperative to improve current forecasting approaches by incorporating reliable data and alternative forecasting targets to better inform decision-makers. Wastewater-based epidemiology (WBE) has emerged as a viable method to track COVID-19 transmission, offering a more reliable metric than reported cases for forecasting critical outcomes like hospitalizations.
View Article and Find Full Text PDFMed Sci (Basel)
December 2024
Department of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.
: Environmental exposures, such as heavy metals, can significantly affect physical activity, an important determinant of health. This study explores the effect of physical activity on combined exposure to cadmium, lead, and mercury (metals), using data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES). Physical activity was measured with ActiGraph GT3X+ devices worn continuously for 7 days, while blood samples were analyzed for metal content using inductively coupled plasma mass spectrometry.
View Article and Find Full Text PDFPhys Rev E
November 2024
Institute of Earthquake Prediction Theory and Mathematical Geophysics, RAS, Profsoyuznaya 84/32, 117997 Moscow, Russia.
We study two prototypical models of self-organized criticality, namely sandpile automata with deterministic (Bak-Tang-Wiesenfeld) and probabilistic (Manna model) dynamical rules, focusing on the nature of stress fluctuations induced by driving-adding grains during avalanche propagation, and dissipation through avalanches that hit the system boundary. Our analysis of stress evolution time series reveals robust cyclical trends modulated by collective fluctuations with dissipative avalanches. These modulated cycles attain higher harmonics, characterized by multifractal measures within a broad range of timescales.
View Article and Find Full Text PDFBMC Glob Public Health
October 2024
Department of Civil and Systems Engineering, Johns Hopkins University, Baltimore, MD, USA.
Background: COVID-19 will not be the last pandemic of the twenty-first century. To better prepare for the next one, it is essential that we make honest appraisals of the utility of different responses to COVID. In this paper, we focus specifically on epidemiologic forecasting.
View Article and Find Full Text PDFPopul Health Metr
December 2024
Max Planck Institute for Demographic Research, Konrad-Zuse-Straße 1, 18057, Rostock, Germany.
Background: In the winter of 2022/2023, excess death estimates for Germany indicated a 10% elevation, which has led to questions about the significance of this increase in mortality. Given the inherent errors in demographic forecasting, the reliability of estimating a 10% deviation is questionable. This research addresses this issue by analyzing the error distribution in forecasts of weekly deaths.
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