AI Article Synopsis
- The study examined the effects of different heating methods and durations on endotoxin in both plasma and pyrogen-free water.
- Heating endotoxin in plasma at 100 degrees C for both 1 and 10 minutes yielded similar results without significant differences in standard curves.
- In contrast, heating for 10 minutes at 75 degrees C resulted in a noticeably less steep curve, while heating at 56 degrees C for 10 minutes led to a completely flat curve; pyrogen-free water showed a similar pattern with curves flattening after just 1 minute of heating.
Article Abstract
Four modes of heating endotoxin in plasma and two different times of heating endotoxin in pyrogen-free water were compared. There were no significant differences in standard curves after heating endotoxin in plasma at 100 degrees C for 1 and for 10 min. However, the standard curve after heating for 10 min at 75 degrees C had a significantly less steep slope, and after heating for 10 min at 56 degrees C, it was completely flat. Heating of endotoxin in pyrogen-free water for 1 min also resulted in the flattening of the standard curve, which was even more pronounced after 10 min of heating.
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| http://dx.doi.org/10.1139/m86-140 | DOI Listing |
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