Recent findings showed the role of late-night eating in metabolic disorders, highlighting the importance of meal timing for health. No evidence is available on the role of meal timing for longevity. The aim of this study was to survey, in a cross-sectional study, meal timing and dietary habits of 68 nonagenarians and centenarians of the Abruzzo region, Italy. Results showed an early dinner (7:13 p.m.) and a calorie restriction lapse of 17.5 h between dinner and the following lunch. The frequency of consumption was high for cereals, vegetables, fruits, and legumes; low for meat, processed meat, and eggs; and negligible for sweets. Subjects were physically active throughout life. Our results support the importance of a daily caloric restriction lapse, hampering nocturnal postprandial stress and optimizing metabolic response, associated with high consumption of plant-based foods and physical activity for the longevity of centenarians from Abruzzo.
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http://dx.doi.org/10.3389/fnut.2022.863106 | DOI Listing |
Alzheimers Dement
December 2024
The Pennsylvania State University, University Park, PA, USA.
Background: Inflammation is a risk factor for cognitive decline, mild cognitive impairment (MCI), and Alzheimer's disease (AD). While past research in laboratory settings suggests that inflammation relates to cognitive decline and MCI status, more research is needed to examine such associations in everyday life. The present work addressed this gap by examining MCI and gender stratified links between circulating inflammatory biomarkers and self-reported prospective memory (PM; i.
View Article and Find Full Text PDFSci Adv
December 2024
McCaig Institute for Bone and Joint Health, University of Calgary, 3280 Hospital Drive NW, Calgary T2N 4Z6, Canada.
Mechanical unloading causes bone loss, but it remains unclear whether disuse-induced changes to bone microstructure are permanent or can be recovered upon reloading. We examined bone loss and recovery in 17 astronauts using time-lapsed high-resolution peripheral quantitative computed tomography and biochemical markers to determine whether disuse-induced changes are permanent. During 6 months in microgravity, resorption was threefold higher than formation.
View Article and Find Full Text PDFPercept Mot Skills
November 2024
Research Institute for Sport and Exercise, University of Canberra, Bruce, ACT, Australia.
Active movement extent discrimination assessment (AMEDA) is a psychophysical task that evaluates proprioception and tactile acuity of the lower limbs, and it is a method of determining sensorimotor ability. Sensorimotor ability is the ability to judge small differences in movement tasks through the process of receiving sensory messages (sensory input) and producing a response (motor output). Participant attention lapses in prior psychophysical studies have been implicated as a cause for increased measurement variance thresholds in these types of assessments.
View Article and Find Full Text PDFBiomed Opt Express
November 2024
Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne 3010, Australia.
confocal microscopy (IVCM) is a widely used technique for imaging the cornea of the eye with a confocal scanning light ophthalmoscope. Cellular resolution and high contrast are achieved without invasive procedures, suiting the study of living humans. However, acquiring useful image data can be challenging due to the incessant motion of the eye, such that images are typically limited by noise and a restricted field of view.
View Article and Find Full Text PDFPurpose: Sleep disruption (SD) impairs sustained attention, and impairment is quantified with the psychomotor vigilance test (PVT) in humans. In rats, food restriction attenuates SD's effects on sustained attention, limiting translation of rodent vigilance tests. The goal of the current study was to determine if a rodent PVT (rPVT) requiring high baseline performance using food restriction and reinforcement is sensitive to the effects of SD.
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