AI Article Synopsis
- Non-pharmaceutical interventions (NPIs) against COVID-19, implemented in March 2020, resulted in a significant reduction in hospitalized community-acquired pneumonia (hCAP) cases in children in France.
- A detailed analysis of 2,972 hCAP cases revealed a 63% drop in monthly cases after NPIs began, with a notable increase in the median age of affected children.
- The study also found that fewer children had high inflammatory markers and there was a trend towards a decrease in pleural effusion cases during the NPI period, suggesting changes in the pathogens causing hCAP.
Article Abstract
Non-pharmaceutical interventions (NPIs) against coronavirus disease 2019 were implemented in March 2020. These measures were followed by a major impact on viral and non-viral diseases. We aimed to assess the impact of NPI implementation in France on hospitalized community-acquired pneumonia (hCAP) frequency and the clinical and biological characteristics of the remaining cases in children. We performed a quasi-experimental interrupted time-series analysis. Between June 2014 and December 2020, eight pediatric emergency departments throughout France reported prospectively all cases of hCAP in children from age 1 month to 15 years. We estimated the impact on the monthly number of hCAP using segmented linear regression with autoregressive error model. We included 2,972 hCAP cases; 115 occurred during the NPI implementation period. We observed a sharp decrease in the monthly number of hCAP after NPI implementation [-63.0% (95 confidence interval, -86.8 to -39.2%); < 0.001]. Children with hCAP were significantly older during than before the NPI period (median age, 3.9 vs. 2.3 years; < 0.0001), and we observed a higher proportion of low inflammatory marker status (43.5 vs. 33.1%; = 0.02). Furthermore, we observed a trend with a decrease in the proportion of cases with pleural effusion (5.3% during the NPI period vs. 10.9% before the NPI; = 0.06). NPI implementation during the COVID-19 (coronavirus disease 2019) pandemic led not only to a strong decrease in the number of hCAP cases but also a modification in the clinical profile of children affected, which may reflect a change in pathogens involved.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980475 | PMC |
| http://dx.doi.org/10.3389/fped.2022.782894 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparing Different Implementation Strategies for Collaborative Dementia Care Management in Terms of Patients' Characteristics, Unmet Needs, and the Impact on Quality of Life and Costs in Germany.
Pharmacoecon Open
December 2024
German Center for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald, Ellernholzstrasse 1-2, 17489, Greifswald, Germany.
Objective: To compare the implementation of collaborative dementia care management (cDCM) across two settings regarding patients' characteristics, unmet needs, and the impact on health-related quality of life (HRQoL) and costs.
Methods: This analysis was based on data from the DCM:IMPact study, implementing cDCM in a physician network (n = 22 practices) and two day care centers (DCC) for community-dwelling persons with dementia over 6 months in Germany. Participants completed comprehensive assessments at baseline and 6 months after, soliciting sociodemographic and clinical characteristics, unmet needs, HRQoL and healthcare resource utilization.
Objective: To investigate a dose-response relationship between the magnitude of decrease in pediatric respiratory tract infections (RTI) during the 2020 implementation of non-pharmaceutical interventions (NPI) and the rise thereafter during NPI lifting.
Study Design: We conducted an interrupted, time-series analysis, based on a multinational surveillance system. All patients <16 years of age coming to medical attention with various symptoms and signs of RTI at 25 pediatric emergency departments from 13 European countries between January 2018 and June 2022 were included.
Rising incidence of gonorrhea in Taiwan amid the COVID-19 pandemic: a nationwide surveillance study.
Sex Health
November 2024
Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City, Taiwan; and Department of Pediatrics, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City, Taiwan; and Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.
Article Synopsis
- The study examines the impact of COVID-19 on the prevalence of sexually transmitted infections (STIs) in Taiwan, focusing on the trends observed from 2015 to 2022.
- Researchers found that despite the pandemic and various public health interventions, gonorrhea notifications significantly increased from an average of 85 per week pre-pandemic to 143 per week during the pandemic, indicating a 68% rise.
- The findings suggest that gonorrhea remains a critical public health issue in Taiwan, as its incidence did not decrease even amidst disruptions to testing and healthcare services.
Effects of nonpharmaceutical interventions during COVID-19 pandemic on pediatric asthma exacerbations and viral infections.
J Allergy Clin Immunol Glob
November 2024
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Ark.
Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in March 2020 led to the implementation of nonpharmaceutical interventions (NPIs) to curb its spread. Studies have shown that adult asthma exacerbations and viral infections decreased during NPI use. However, few studies have shown the effects of NPIs on pediatric asthma exacerbations and infections during and after the pandemic.
View Article and Find Full Text PDFKnowledge, Attitude, and Practice of Care Providers Toward Non-Pharmacological Intervention for Managing Behavioural and Psychological Symptoms in Australian Aged Care Residents with Dementia: A Cross-Sectional Survey.
Clin Gerontol
October 2024
Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia.
Article Synopsis
- This study evaluated how well healthcare professionals and caregivers understand and implement non-pharmacological interventions (NPIs) to manage behavioral and psychological symptoms of dementia in Australian aged care facilities.
- An online survey of 96 staff members revealed that while many were familiar with NPIs, a significant portion felt there was inadequate funding and resources to properly implement them.
- The findings suggest that barriers like limited funding, personnel, and skepticism about NPIs hinder their use, indicating a need for better education, training, and increased support for these interventions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!