A covalent organic framework with a self-contained light source for photodynamic therapy.

Chem Commun (Camb)

College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education Shandong Normal University, Jinan 250014, People's Republic of China.

Published: April 2022

External light-independent antitumor PDT is successfully realized with a covalent organic framework (COF)-based host-guest nanosystem. Its highly effective antitumor behavior is fully demonstrated by both HO-overexpressed 4T1 and HO-less expressed HCT116 and MCF-7 xenograft models.

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Source
http://dx.doi.org/10.1039/d2cc01397eDOI Listing

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