Purpose: Investigator feedback was used to assess the clinical use of the LipiFlow System with the new translucent Activator Clear to successfully complete LipiFlow treatments.
Patients And Methods: This was a prospective, open-label clinical investigation. A total of 88 eyes (44 subjects) were treated using the LipiFlow System with the new Activator Clear. Subjects diagnosed with bilateral meibomian gland dysfunction (MGD) were enrolled in the study. Each investigator performed a complete LipiFlow treatment with the translucent Activator on both eyes of each subject. Investigators completed a questionnaire assessing the clinical use of the Activator Clear on a 5-point scale (1 - very difficult or strongly disagree, 3 - neutral, 5 - very easy or strongly agree).
Results: The new translucent Activator provided successful LipiFlow treatments in 100% of cases, with 95% confidence interval of (96%, 100%). Additionally, the investigators agreed or strongly agreed that the translucent components of the Activator Clear made it easy to access and position the activator with confidence on the subject's eye.
Conclusion: The overall investigators' impressions on usage and functionality of LipiFlow System with the translucent Activator were very positive. The Activator Clear enables doctors with efficient and confident positioning around patient eyelids to ensure successful LipiFlow treatment when used as indicated.
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http://dx.doi.org/10.2147/OPTH.S354738 | DOI Listing |
Cureus
November 2024
Internal Medicine, Kettering Health Network, Kettering, USA.
Aquagenic syringeal acrokeratoderma (ASA) is a rare dermatological condition characterized by the transient appearance of edematous, white, translucent papules on the palms following water exposure. While the condition is most commonly associated with cystic fibrosis (CF) and predominantly affects young women, this report presents a unique case in a 24-year-old man without a history of cystic fibrosis. The patient reported a 10-month history of painful, pruritic eruptions on the hands following exposure to water.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Dairy and Food Science, South Dakota State University, Brookings, SD 57007, USA. Electronic address:
Plastic packaging has increased concerns about human health and the ecosystem due to non-biodegradability. Several biopolymers, such as cellulose, starch, and proteins, are being explored, and cellulosic residue from agricultural biomass is suitable to overcome this predicament. Herein, cellulosic residue fibers (ACR) extracted from alfalfa were used to prepare biodegradable films by solubilizing them in ZnCl solution and crosslinking the chains with calcium ions (CaCl) and sorbitol.
View Article and Find Full Text PDFAAPS PharmSciTech
December 2024
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKMs NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, Maharashtra, 400056, India.
This research aimed to develop a mupirocin-doped α-cellulose nanopaper (MDAC-NP) as a wound dressing to accelerate wound healing while limiting localized bacterial growth. The α-cellulose nanofibrils suspension was prepared by ultrasonication followed by microfluidization and subsequently doped with 0.05% w/v mupirocin to prepare nanopaper (MDAC-NP-A).
View Article and Find Full Text PDFCureus
November 2024
Department of Preventive Dentistry, Umm Al-Qura University, Makkah, SAU.
Objectives: Recently, dental esthetics have increasingly emphasized appearance, with tooth shade selection complicated by the enamel and dentin's translucency and opacity. Smartphone cameras are useful for shade matching. Currently, no study has directly compared the accuracy of this method.
View Article and Find Full Text PDFPeerJ
December 2024
Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
Background: Chronic lymphocytic leukemia (CLL) is a common adult leukemia characterized by the accumulation of neoplastic mature B cells in blood, bone marrow, lymph nodes, and spleen. The disease biology remains unresolved in many aspects, including the processes underlying the disease progression and relapses. However, studying CLL poses a considerable challenge due to its complexity and dependency on the microenvironment.
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