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Challenges Faced by Behavioral Genetic Studies: Researchers Perspective from the MENA Region. | LitMetric

AI Article Synopsis

  • Behavioral genetic studies are crucial for understanding how genetic variations affect human behavior, but they raise ethical concerns, particularly in sensitive cultural contexts like the MENA region.
  • Researchers from the MENA region discussed challenges like recruitment ethics, obtaining informed consent, and protecting privacy, with cultural norms and social stigma further complicating these issues.
  • To improve the situation, the study suggests creating regulations for genetic research, increasing public awareness, and ensuring responsible research practices to address the unique challenges faced in these populations.*

Article Abstract

Background: Behavioral genetic studies are important for the understanding of the contribution of genetic variations to human behavior. However, such studies might be associated with some ethical concerns.

Methods: In the current study, ethical challenges related to studies of genetic variations contributing to human behavior were examined among researchers. To achieve the study purpose, the Middle East and North Africa (MENA) region researchers were taken as an example, where the after- mentioned ethical challenges were discussed among a group of researchers, who were the participants of an online forum. Discussions and responses of the participants were monitored and were later qualitatively analyzed.

Results: Discussions revealed that several ethical challenges, including subjects' recruitment, the difficulty of obtaining informed consents, and issues of privacy and confidentiality of obtained data as information leakage, in this case, will lead to social stigma and isolation of the participants and their immediate family members. Jordanian social and cultural norms, faith, and the tribal nature of the population were raised as a major challenge that might face conducting behavioral genetic studies in the Arab populations of the MENA. The lack of regulation related to the conduction of genetic studies, misunderstanding, and misuse of genetic information are other challenges. A full explanation of genetic research and the current and future possible benefits/risks of such research could be potential solutions.

Conclusion: In conclusion, the MENA populations are tackled with major challenges in relation to conducting research studies in genetics/antisocial behavior field/s. Establishment of guidelines related to genetic studies, capacity building, increasing public awareness about the importance of genetic testing, and enhancing responsible conduct of research will facilitate the conduct of such sensitive studies in the future in the region.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905636PMC
http://dx.doi.org/10.2174/1389202923666211216162141DOI Listing

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