[This corrects the article DOI: 10.1093/braincomms/fcab104.].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978862 | PMC |
| http://dx.doi.org/10.1093/braincomms/fcac067 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Manifestations.
Alzheimers Dement
December 2024
Department of Neurology, National Neuroscience Institute, Singapore, Singapore, Singapore, Singapore.
Background: Epilepsy is associated with increased risk for dementia, which adversely impacts the quality of life for patients and their families. Mild cognitive impairment (MCI) is the prodromal stage of dementia offering an important window for intervention. However, the epilepsy related risk factors for MCI are not well understood.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Boston, MA, USA.
Background: Orientation in time, space, and person is often impaired in Alzheimer's disease dementia. Subtle changes in orientation may occur in prodromal and preclinical disease stages. Here we aim to assess the cross-sectional association between individuals' orientation to their own world, as measured with a novel AI-based paradigm, and Alzheimer's disease biomarkers (amyloid and tau) in cognitively unimpaired older adults.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: The National Institutes of Health Toolbox for Assessment of Neurological and Behavioral Function (NIHTB) was developed to address the need for a brief yet comprehensive instrument to facilitate more uniform assessment in large-scale research studies. Here, we investigated whether the cognitive measures of the NIHTB detect cognitive decline in biomarker-confirmed Alzheimer's disease (AD).
Method: We used data from N = 178 participants (age 76.
The misclassification of depression and anxiety disorders in the multiple sclerosis prodrome: A probabilistic bias analysis.
Ann Epidemiol
December 2024
Medicine (Neurology), University of British Columbia and The Djavad Mowafaghian Centre for Brain Health, Vancouver, BC, Canada.
Background: Studies suggest that depression/anxiety form part of the multiple sclerosis (MS) prodrome. However, several biases have not been addressed. We re-examined this association after correcting for: (i) misclassification of individuals not seeking healthcare, (ii) differential surveillance of depression/anxiety in the health system, and (iii) misclassified person-time from using the date of the first MS-related diagnostic claim (i.
View Article and Find Full Text PDFIctal SPECT Imaging Findings in Parkinson's Disease with Rapid Eye Movement Sleep Behavior Disorder.
Mov Disord Clin Pract
December 2024
Department of Neurology and Nuclear Medicine, University of Stellenbosch, Cape Town, South Africa.
Background: Rapid eye movement sleep behavior disorder (RBD) is an established prodrome and symptom of synucleinopathies. The pathophysiology of this disorder has been well studied but there is a lack of functional imaging data to illustrate the dysfunction in vivo.
Objectives: We aimed to investigate the functional changes of RBD, by performing ictal REM sleep SPECT, comparing subjects with Parkinson's Disease (PD) and evidence of RBD to subjects with PD and no RBD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!