Three-dimensional printing is a still-emerging technology with high impact for the medical community, particularly in the development of tissues for the clinic. Many types of printers are under development, including extrusion, droplet, melt, and light-curing technologies. Herein we discuss the various types of 3D printers and their strengths and weaknesses concerning tissue engineering. Despite the advantages of 3D printing, challenges remain in the development of large, clinically relevant tissues. Advancements in bioink development, printer technology, tissue vascularization, and cellular sourcing/expansion are discussed, alongside future opportunities for the field. Trends regarding in situ printing, personalized medicine, and whole organ development are highlighted.
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http://dx.doi.org/10.1146/annurev-chembioeng-092220-015404 | DOI Listing |
Purpose: To create tridimensional (3D) anatomical models of diaphyseal fractures in dogs (3D AMDFD) and to evaluate the models from their radiographs.
Methods: The study consisted of six stages: preparation of femur from a healthy dog cadaver; digitalization of the bone through a 3D scanner and creation of the base model; creation of a 3D AMDFD based on the image of the base model, 3D modeling carried out to reproduce five different types of diaphyseal fractures; printing the models produced on a 3D printer with a thermoplastic material; insertion of neodymium magnets in the fracture line to allow the assembly and disassembly of the parts; and radiography of 3D AMDFD in lateromedial and craniocaudal positions.
Results: The base model and 3D AMDFD had high precision in the replication of bone structures, like the bone in natura.
Bioengineering (Basel)
November 2024
Department of Prosthodontics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Accurate implant placement is essential for achieving successful outcomes. To aid in this, digitally designed surgical guides have been introduced. Both closed-sleeve and open-sleeve designs are commonly utilized.
View Article and Find Full Text PDFInt J Pharm
January 2025
NHC Key Laboratory of Reproductive Health Engineering Technology Research, National Research Institute for Family Planning (CN), Beijing, China. Electronic address:
In recent years, 3D printers have grown strongly in drug delivery and personalised medicine, being used more and more widely. In medicine, 3DP technology can advance personalised medicine and design dosage forms to regulate the drug release rate. This review gives an overview of the 3D printing for controlled-release pharmaceuticals, detailing the technical principles, common types (including extrusion, powder, liquid, and sheet lamination-based systems), drug release control mechanisms (e.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Prosthodontics, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
With the advancement of digital technology, it has become possible to record jaw motion using intraoral scanners. However, there is a paucity of studies evaluating their accuracy. Twelve sets of scan data from 12 individuals were additively manufactured using a 3D printer and 3D-printable material.
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