AI Article Synopsis
- The HEART Pathway is a protocol used in emergency departments to help assess the risk of heart issues in patients and its effectiveness across different age groups, particularly older adults, is under investigation.
- A study analyzed data from over 8,400 patients, revealing that a smaller percentage of older adults were classified as low-risk compared to younger groups, with only 7.4% of older adults deemed low-risk.
- Despite the HEART Pathway showing high sensitivity for serious outcomes among older adults, it did not lead to reduced hospitalization rates in this age group, suggesting a need for further enhancements in its application for older patients.
Article Abstract
Background: The HEART Pathway is a validated protocol for risk stratifying emergency department (ED) patients with possible acute coronary syndrome (ACS). Its performance in different age groups is unknown. The objective of this study is to evaluate its safety and effectiveness among older adults.
Methods: A pre-planned subgroup analysis of the HEART Pathway implementation study was conducted. This prospective interrupted time series accrued adult ED patients with possible ACS who were without ST-elevation across three US sites from 11/2013-01/2016. After implementation, providers prospectively used the HEART Pathway to stratify patients as low-risk or non-low-risk. Patients were classified as older adults (≥65 years), middle-aged (46-64 years), and young (21-45 years). Primary safety and effectiveness outcomes were 30-day death or MI and hospitalization at 30 days, determined from health records, insurance claims, and death index data. Fisher's exact test compared low-risk proportions between groups. Sensitivity for 30-day death or MI and adjusted odds ratios (aORs) for hospitalization and objective cardiac testing were calculated.
Results: The HEART Pathway implementation study accrued 8474 patients, of which 26.9% (2281/8474) were older adults, 45.5% (3862/8474) middle-aged, and 27.5% (2331/8474) were young. The HEART Pathway identified 7.4% (97/1303) of older adults, 32.0% (683/2131) of middle-aged, and 51.4% (681/1326) of young patients as low-risk (p < 0.001). The HEART Pathway was 98.8% (95% CI 97.1-100) sensitive for 30-day death or MI among older adults. Following implementation, the rate of 30-day hospitalization was similar among older adults (aOR 1.25, 95% CI 1.00-1.55) and cardiac testing increased (aOR 1.25, 95% CI 1.04-1.51).
Conclusion: The HEART Pathway identified fewer older adults as low-risk and did not decrease hospitalizations in this age group.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378522 | PMC |
| http://dx.doi.org/10.1111/jgs.17777 | DOI Listing |
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