Comparing free-space and fiber-coupled detectors for Fabry-Pérot-based all-optical photoacoustic tomography.

J Biomed Opt

European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Unit, Heidelberg, Germany.

Published: April 2022

Significance: Highly sensitive detection is crucial for all-optical photoacoustic (PA) imaging. However, free-space optical detectors are prone to optical aberrations, which can degrade the pressure sensitivity and result in deteriorated image quality. While spatial mode-filtering has been proposed to alleviate these problems in Fabry-Pérot-based pressure sensors, their real functional advantage has never been properly investigated.

Aim: We rigorously and quantitatively compare the performance of free-space and fiber-coupled detectors for Fabry-Pérot-based pressure sensors.

Approach: We develop and characterize a quantitative correlative setup capable of simultaneous PA imaging using a free space and a fiber-coupled detector.

Results: We found that fiber-coupled detectors are superior in terms of both signal level and image quality in realistic all-optical PA tomography settings.

Conclusions: Our study has important practical implications in the field of PA imaging, as for most applications and implementations fiber-coupled detectors are relatively easy to employ since they do not require modifications to the core of the system but only to the peripherally located detector.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983068PMC
http://dx.doi.org/10.1117/1.JBO.27.4.046001DOI Listing

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