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Gallbladder carcinoma in the era of artificial intelligence: Early diagnosis for better treatment.
World J Gastrointest Oncol
January 2025
Department of Anatomy, Division of Human Biology, School of Medicine, IMU University, Kuala Lumpur 57000, Kuala Lumpur, Malaysia.
Gallbladder carcinoma (GBC) is the most common malignant tumor of biliary tract, with poor prognosis due to its aggressive nature and limited therapeutic options. Early detection of GBC is a major challenge, with most GBCs being detected accidentally during cholecystectomy procedures for gallbladder stones. This letter comments on the recent article by Deqing in the , which summarized the various current methods used in early diagnosis of GBC, including endoscopic ultrasound (EUS) examination of the gallbladder for high-risk GBC patients, and the use of EUS-guided elastography, contrast-enhanced EUS, trans-papillary biopsy, natural orifice transluminal endoscopic surgery, magnifying endoscopy, choledochoscopy, and confocal laser endomicroscopy when necessary for early diagnosis of GBC.
View Article and Find Full Text PDFLaparoscopic cholecystectomy for triple gallbladder malformation: A comprehensive case report and literature review.
Medicine (Baltimore)
January 2025
Hepatobiliary Surgery, Hepatobiliary Disease Laboratory, Kailuan General Hospital, Tangshan, Hebei Province, China.
Rationale: Triple gallbladder is a rare congenital anatomical abnormality because of the incomplete regression of rudimentary bile ducts and is often not found until it is accidentally detected during imaging research.
Patient Concerns: We report a rare case of triple gallbladder malformation and review the English literature on biliary tract variation caused by gallbladder malformation. The diagnosis, treatment, and postoperative situation of the patients were summarized and analyzed.
Usefulness of Endoscopic Retrograde Cholangiopancreatography (ERCP)-Related Procedures for Gallstone Pancreatitis.
Cureus
August 2024
Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, JPN.
Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST) are said to be useful procedures for gallstone pancreatitis. However, there have been few reports on a large number of patients to whom they were used. The clinical usefulness of ERCP and EST is herein examined retrospectively.
View Article and Find Full Text PDFUnusual case of Niemeier type II gallbladder perforation: case report and literature review.
J Int Med Res
June 2024
Department of Hepatobiliary Surgery, Xiaolan People's Hospital of Zhongshan (The Fifth People's Hospital of Zhongshan), Zhongshan, Guangdong Province, China.
Niemeier type II gallbladder perforation (GBP) is caused by inflammation and necrosis of the gallbladder wall followed by bile spilling into the abdominal cavity after perforation. The gallbladder then becomes adhered to the surrounding inflammatory tissue to form a purulent envelope, which communicates with the gallbladder. At present, the clinical characteristics and treatment of type II GBP are not well understood and management of GBP remains controversial.
View Article and Find Full Text PDFAmanitin determination in bile samples by UHPLC-MS: LR-MS and HR-MS analytical performance.
J Pharm Biomed Anal
September 2024
University of Coimbra, Faculty of Pharmacy, Health Science Campus, Azinhaga de Santa Comba, Coimbra 3000-548, Portugal; REQUIMTE/LAQV, R. D. Manuel II, Apartado, Porto 55142, Portugal. Electronic address:
Consumption of misidentified foraged mushrooms containing bicyclic amanitin octapeptides is a worldwide public health and veterinary problem, being considered one of the deadliest accidental human and canine food ingestion due to acute liver failure (ALF). Reversal of advanced ALF and complete clinical recovery can be achieved following definitive removal of accumulated amatoxin laden bile from the gallbladder. An accurate means of quantifying amanitin content in aspirated bile is, therefore, urgently needed.
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