Background: Since 1976, several JE outbreaks have been reported from most of the districts of Assam.
Objectives: The present study aims to conduct a descriptive and spatial analysis to understand the spatiotemporal distribution of JE cases of Dibrugarh district.
Methods: Spatiotemporal distribution of JE cases from 2014 to 2018 at village level was described in maps using Geographical Information System. Spatial association between JE reporting places in the study area has been analyzed using spatial statistics analytical techniques. Temporal distribution of JE cases from 2014 to 2018 for different variable were described in tables.
Results: During the period 2014-2018, incidence rate of JE cases ranged between 2.7/100,000 and 5.9/100,000 population and highest case fatality rate was 18.3% in 2014. Highest numbers of JE cases were reported in the age group 0-10 years. Most of the JE cases were from rural areas (84.2%). There was a seasonal pattern of JE which peaked in July. There were hotspots around Dibrugarh Municipality area, Duliajan oil town, Hatiali gaon, Naharkatiya chah bagicha, Nagaon Dhadumia gaon, and Nahortoli Tea Estate.
Conclusion: On the basis of the study, JE hotspots can be identified that would help health authorities to further investigate and identify the factors responsible for its occurrence.
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http://dx.doi.org/10.4103/ijph.ijph_1296_21 | DOI Listing |
Br J Gen Pract
December 2024
University College London, London, United Kingdom.
Background: Evidence on whether general practice rates of investigation in symptomatic patients using chest x-ray (CXR) affects outcomes is equivocal.
Aim: Determine if there is an association between rates of general practice (GP) requested CXR and lung cancer outcomes.
Design And Setting: Retrospective observational study (England) Methods: Cancer registry data for patients diagnosed with lung cancer 2014-2018 was linked to data on GP CXRs 2013-2017.
Int J Surg Case Rep
December 2024
Department of Otorhinolaryngology, Aarhus University Hospital, Aarhus N, Denmark.
Introduction And Importance: Primary hyperparathyroidism (PHPT) is a frequent complication to multiple endocrine neoplasia type 1 (MEN1), presenting challenges due to increased risk of multi-gland disease and recurrence post parathyroidectomy (PTX). This case report examines the management of PHPT in a MEN1 patient, emphasizing possible benefits from intraoperative parathyroid autofluorescence imaging (AF).
Case Presentation: A 21-year-old woman with MEN1 presented with mild hyperparathyroidism symptoms in 2014.
J Pineal Res
January 2025
Instituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
Tumor necrosis factor (TNF) is a biomarker of inflammation whose levels are elevated in patients with several diseases associated with dysregulation of the immune response. The main limitations of currently used anti-TNF therapies are the induction of immunodepression, which in many cases leads to serious adverse effects such as infection and cancer, and the inability to cross the blood-brain barrier in neuroinflammatory conditions. Melatonin, in addition to being a chronobiotic compound, is widely known for its antioxidant and immunomodulatory capacity to control inflammatory processes in different pathological contexts.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, Connecticut, United States of America.
Objective: Predicting neonatal survival is essential for targeting interventions to reduce neonatal mortality. Pacific Islanders have been underrepresented in existing prediction tools and have unique, maternal obesity-related risk factors for both preterm birth and neonatal mortality. Using neonatal sex, birth weight, and gestational age, we developed a graphical tool for neonatal survival among Pacific Islander singletons in the United States.
View Article and Find Full Text PDFJ Autism Dev Disord
December 2024
Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.
To examine the effect of using Virtual Reality distraction on salivary cortisol levels in children with Autism Spectrum Disorders (ASD) during routine dental treatments. A randomized cross-over study was designed and children with a known diagnosis of ASD, between 8 and 15 years of age, requiring routine, non-invasive dental treatments, were recruited. They were divided into 2 groups (group 1 and group 2) and scheduled for dental treatments using conventional behavior management and/or VR distraction techniques in their first and second dental visit, accordingly.
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