AI Article Synopsis
- Researchers found that marginal zone B cells (MZBs) can take MHC class II molecules from dendritic cells (DCs).
- This process occurs during a specific immune response known as a complement-dependent reaction.
- By using these stolen MHCII complexes, MZBs may enhance or modify T cell activation differently than how dendritic cells do.
Article Abstract
In a recent paper, Schriek et al. show that, in a complement-dependent reaction, marginal zone B cells (MZBs) steal MHC class II (MHCII) from dendritic cells (DCs). Activation of T cells by stolen MHCII complexes potentially allows MZBs to augment or regulate T cell activation in ways that are distinct from DCs.
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| http://dx.doi.org/10.1016/j.it.2022.03.008 | DOI Listing |
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