AI Article Synopsis
- The study assessed a 3D-printed ventilator's durability, sterilization, and performance, particularly during the COVID-19 pandemic where ventilator supply chains were challenged.
- Testing involved dropping the ventilator from a height and autoclaving it, with results showing no significant degradation in its performance metrics.
- The CRISIS ventilator demonstrated good minute ventilation capabilities and has potential for real-world application, although more in-vivo testing is recommended.
Article Abstract
Background: The COVID-19 pandemic revealed flaws in the stockpiling and distribution of ventilators. In this study, we assessed the durability, sterilizability, and performance of a 3D-printed ventilator.
Methods: SLS-printed devices were dropped from 1.83 m and autoclaved before evaluation on a COVID-19 simulated patient. The respiratory performance of an extrusion-printed device was studied using a variable compliance model. Ranges of sustainable respiratory rates were evaluated as a function of tidal volume.
Results: Autoclaving and dropping the device did not negatively impact minute ventilation or PIP for sustained ventilation. Equivalence was significant across all measures except for comparing the autoclaved and dropped with p = 0.06. Extrusion produced ventilators achieved minute ventilation ranging from 4.1 to 12.2 L/min for all simulated compliances; there was an inverse correlation between tidal volume and respiratory rate.
Conclusion: The CRISIS ventilator is a durable, sterilizable, and reusable 3D-printed ventilator using off-the-shelf materials which could be employed variety of adult lung diseases. Further in-vivo testing is needed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915621 | PMC |
| http://dx.doi.org/10.1016/j.amjsurg.2022.02.064 | DOI Listing |
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