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| http://dx.doi.org/10.4097/kja.22098 | DOI Listing |
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Factors associated with postoperative shivering in patients with maintained core temperature after surgery.
JA Clin Rep
November 2024
Department of Anesthesiology and Critical Care Medicine, Kyushu University Graduate School of Medicine, Fukuoka, Japan.
Background: Postoperative shivering is mainly associated with low body temperature. However, postoperative shivering can develop even at normal or high core temperatures. This study aimed to investigate the factors associated with postoperative shivering in patients with maintained core temperature after surgery.
View Article and Find Full Text PDFNeural correlates of systemic lidocaine administration in healthy adults measured by functional MRI: a single arm open label study.
Br J Anaesth
October 2024
Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA; Department of Anesthesiology, Surgical Service Line, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Introduction: Intravenous lidocaine is increasingly used as a nonopioid analgesic, but how it acts in the brain is incompletely understood. We conducted a functional MRI study of pain response, resting connectivity, and cognitive task performance in volunteers to elucidate the effects of lidocaine at the brain-systems level.
Methods: We enrolled 27 adults (age 22-55 yr) in this single-arm, open-label study.
Unconscious classification of quantitative electroencephalogram features from propofol versus propofol combined with etomidate anesthesia using one-dimensional convolutional neural network.
Front Med (Lausanne)
September 2024
Department of Anesthesiology, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- Scientists created a computer program called a convolutional neural network (CNN) to help understand brain activity from EEG signals while patients are asleep from anesthesia.
- They tested this program on 40 surgery patients, dividing them into two groups to receive different types of anesthesia and then analyzed their brain wave patterns.
- The CNN was really good at telling when the patients were unconscious, doing better than other methods, and showed that certain brain wave measurements were important for monitoring consciousness during surgery.
Predictive pharmacodynamic performance of the Eleveld pharmacokinetic-pharmacodynamic model for propofol: comparison of predicted and measured bispectral index.
Br J Anaesth
October 2024
University of Cape Town Department of Anaesthesia and Perioperative Medicine, Cape Town, South Africa. Electronic address:
Background: The Eleveld pharmacokinetic-pharmacodynamic model for propofol predicts bispectral index (BIS) processed electroencephalogram values from estimated effect-site concentrations. We investigated agreement between measured and predicted BIS values during total intravenous anaesthesia (TIVA).
Methods: Forty participants undergoing lower limb surgery received TIVA using remifentanil target-controlled infusions and propofol by manually controlled, target-guided infusions based upon the Eleveld model and directed by two pharmacokinetic computer simulation applications: PKPD Tools and StelSim.
Relationship between intraoperative requirement for anesthetics and postoperative analgesic consumption in laparoscopic colectomy: a randomized controlled double-blinded study.
Anesth Pain Med (Seoul)
April 2024
Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, Jeonju, Korea.
Background: This study investigated the relationship between intraoperative requirement for an inhalational anesthetic (sevoflurane) or an opioid (remifentanil) and postoperative analgesic consumption.
Methods: The study included 200 adult patients undergoing elective laparoscopic colectomy. In the sevoflurane group, the effect-site concentration of remifentanil was fixed at 1.
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