This review provides a summary of important, completed and published clinical trials, together with interesting and important running RCTs in pancreatic surgery.Randomised controlled studies (RCT) are one of the most important sources of new evidence for the treatment of cancer patients. This is particularly the case for pancreas surgery, where complications are comparatively common and serious and innovative surgical techniques and peri-interventional innovations are needed that could reduce morbidity and mortality. Although there are many very different methodological challenges in performing surgical RCTs, large surgical RCTs of high scientific quality have been completed during the last 10 years.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1055/a-1765-4402 | DOI Listing |
Neurosurg Rev
January 2025
Department of Neurosurgery, Hospital Heliópolis, São Paulo, Brazil.
Basal ganglia hemorrhage (BGH) is a prevalent site for intracerebral hemorrhage. Although neuroendoscopy (NE) surgery has emerged as a less invasive alternative to craniotomy (CT), the optimal surgical method remains debatable. This systematic review and meta-analysis aimed to compare the efficacy and safety of NE versus CT in the management of BGH.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Intensive Care Unit, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Background: This study aimed to compare the effectiveness and safety of neuromuscular blockers, mesenchymal stem cells (MSC), and inhaled pulmonary vasodilators (IV) for acute respiratory distress syndrome through a network meta-analysis of randomized controlled trials (RCTs).
Methods: We searched Chinese and English databases, including China National Knowledge Infrastructure, The Cochrane Library, PubMed, and EMbase, with no time restrictions. We conducted a network meta-analysis and reported the results according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.
PLoS One
January 2025
Orthopedics Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Objective: The objective of this systematic review and meta-analysis is to clarify the rehabilitation efficacy of virtual reality (VR) balance training after anterior cruciate ligament reconstruction (ACLR).
Methods: This meta-analysis was registered in PROSPERO with the registration number CRD42024520383. The electronic databases PubMed, Web of Science, Cochrane Library, MEDLINE, Embase, China National Knowledge Infrastructure, Chinese Biomedical Literature, China Science and Technology Journal Database, and Wanfang Digital Periodical database were systematically searched to identify eligible studies from their inception up to January 2024.
Cochrane Database Syst Rev
January 2025
Cochrane Kidney and Transplant, Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, Australia.
Background: Cytomegalovirus (CMV) is a significant cause of morbidity and death in solid organ transplant recipients. Pre-emptive treatment of patients with CMV viraemia using antiviral agents has been suggested as an alternative to routine prophylaxis to prevent CMV disease. This is an update of a Cochrane review first published in 2006 and updated in 2013.
View Article and Find Full Text PDFInt J Surg
December 2024
Wales Kidney Research Unit, Division of Infection and Immunity, Cardiff University, United Kingdom.
Background: Transplantation significantly improves the quality of life for patients with chronic kidney disease. Despite various educational strategies being assessed, the optimal approach to overcome barriers to kidney transplantation remains unclear.
Materials And Methods: The authors conducted a systematic review and network meta-analysis (NMA) of randomized controlled trials (RCTs) comparing educational interventions to improve kidney transplantation access.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!