AI Article Synopsis
- Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are aggressive tumors that can appear in both bone and soft tissues, and they represent different forms of the same condition with various neuroectodermal features.
- This text discusses a unique case of a 9-year-old girl with primary extraskeletal ES/PNET located on her tongue, which is a rare occurrence.
- The girl was treated with surgery followed by six cycles of adjuvant chemotherapy (OPEC regimen), and she is currently tumor-free, highlighting the effectiveness of her comprehensive treatment plan.
Article Abstract
Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are high grade malignant small round cell tumors presenting in both skeletal and extraskeletal anatomic locations. Actually, they are the same entity showing varying degrees of neuroectodermal differentiation. Very few cases of peripheral PNET (pPNET) of the tongue was reported in medical literature. Here, we first report a case of primary extraskeletal ES/pPNET in the tongue of a 9-years old girl. The result of immunohistochemical analysis showed the membranous positive for CD99 and Vimentin. The girl underwent radical surgical treatment and received six cycles of OPEC regimen adjuvantchemotherapy without radiotherapy, and now she is remaining tumor-free survival. The individual comprehensive therapy shows a good curative effect.
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| http://dx.doi.org/10.1016/j.oraloncology.2022.105818 | DOI Listing |
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