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Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection caused by Basidiobolus ranarum, a saprophytic fungus that belongs to the class of Basidiobolomycetes. It mainly infects immunocompetent individuals and is mainly found in arid tropical and subtropical regions, including Southwestern America, Saudi Arabia, Africa, and Asia. Not surprisingly, a great number of human infections have been reported from these warm, humid climate regions that are felicitous for the growth of this fungus, especially from the southern region of Saudi Arabia and Arizona in the United States of America.

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Basidiobolomycosis is an uncommon fungal infection that has been reported in the literature mainly as a cause of infection in the skin and subcutaneous tissue. Intraabdominal infections have been reported in tropical and subtropical areas in the Middle East, such as Iran and Saudi Arabia, and in the United States. Our patient was a 6-year-old girl with cystic fibrosis and celiac disease who was referred to our department with a history of chronic abdominal pain.

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Article Synopsis
  • Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection that affects primarily healthy individuals, often leading to diagnostic difficulties due to its nonspecific symptoms.
  • In a case report, a five-year-old boy was treated for both intestinal intussusception and appendiceal basidiobolomycosis, which is an unusual occurrence.
  • The boy underwent laparoscopic surgery to address the intussusception, and the resected appendix was found to contain fungal organisms, ultimately leading to his full recovery with antifungal treatment.
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Background: Basidiobolus ranarum belongs to the Entomophthorales order and the Zygomycetes class. This fungus is an environmental saprophyte that can be found in soil and rotting vegetables.Primarily restricted to tropical regions including Asia, Africa, and South America.

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