Sarcopenia definition: Does it really matter? Implications for resistance training.

Ageing Res Rev

Institute for Health and Sport (IHES), Victoria University, Melbourne, VIC, Australia; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, Australia; Western Health and the University of Melbourne, Department of Medicine, Footscray, VIC, Australia. Electronic address:

Published: June 2022

AI Article Synopsis

  • Sarcopenia is the loss of muscle mass, strength, and function in older adults, leading to increased risks of falls, fractures, and lower quality of life, and has recently been classified as a disease.
  • There are multiple definitions for diagnosing sarcopenia, primarily focusing on low muscle mass, strength, and physical performance, but discrepancies in criteria can cause confusion in diagnosis.
  • While no drugs exist to treat sarcopenia, resistance training is an effective way to improve muscle-related outcomes, and the focus should be on optimizing resistance training prescriptions and long-term adherence instead of changing the definitions of sarcopenia.

Article Abstract

The loss of muscle mass, strength and function, known as sarcopenia, is common in older adults, and is associated with falls, fractures, cardiometabolic diseases, and lower quality of life. Sarcopenia can also occur secondarily to chronic diseases. Recently, sarcopenia was recognized as a disease with an International Classification of Disease (ICD) code, yet, at least five definitions for its clinical identification exist. Most definitions include three themes: low muscle mass, strength and physical performance. However, the definitions vary by the number of themes needed to diagnose sarcopenia and, within each theme various parameters and cut-off levels exist. The lack of consensus on what constitutes a diagnosis can create confusion and hesitation in sarcopenia diagnosis. Currently, no pharmacological treatment exists for sarcopenia. Resistance training (RT) is safe and effective to improve muscle mass, strength and physical performance in older adults and clinical populations. Based on current guidelines, whether an individual is defined as "sarcopenic", or not, does not change the way RT is prescribed. Here, we present evidence and the inconsistencies in sarcopenia definitions and recommend that focus should be on optimizing ways to prescribe RT and increase long-term adherence, rather than on slight modifications to sarcopenia definitions.

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Source
http://dx.doi.org/10.1016/j.arr.2022.101617DOI Listing

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