Transition-metal-free three-component coupling approach to QUINAP derivatives.

Org Biomol Chem

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.

Published: April 2022

The aluminum(III) triflate catalyzed three-component coupling reaction of alkynes, amines and phosphorylated aryl aldehydes to access phosphoryl quinoline derivatives has been developed. The reaction proceeds in a simple system without the use of transition metals, ligands or additives, thus making it attractive for the fast preparation of a variety of new potential N-P bidentate ligands.

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Source
http://dx.doi.org/10.1039/d1ob02504jDOI Listing

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