Perioperative red blood cell transfusions are common. Antigen screening, performed via indirect Coombs test, is required prior to red blood cell transfusion. False-negative test results can lead to acute or delayed hemolytic transfusion reactions. This case report emphasizes the importance of using life-long alerts in a hospital's electronic medical record system for patients with positive antigen screening to prevent false-negative preoperative antigen results from leading to hemolytic transfusion reactions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958146PMC
http://dx.doi.org/10.7759/cureus.22561DOI Listing

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