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AADB: A Manually Collected Database for Combinations of Antibiotics With Adjuvants.
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Antimicrobial resistance is a global public health concern. The lack of innovations in antibiotic development has led to renewed interest in antibiotic adjuvants. However, there is no database to collect antibiotic adjuvants.
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Department of Respiratory Medicine, The First Hospital of Jilin University, Changchun, China.
Genetic analysis of acidocin B, a novel bacteriocin produced by Lactobacillus acidophilus.
Microbiology (Reading)
July 1995
TNO Nutrition and Food Research Institute, Department of Molecular Genetics and Genetechnology, Rijswijk, The Netherlands.
The genes encoding the production of acidocin B, a bacteriocin produced by Lactobacillus acidophilus strain M46 which is active against Listeria monocytogenes, Clostridium sporogenes, Brochothrix thermosphacta, Lactobacillus fermentum and Lactobacillus delbrueckii subsp. bulgaricus, but inactive against most other Lactobacillus species, were previously localized on a 4 kb XbaI-HindIII fragment of plasmid pCV461. In the present work, DNA sequence analysis revealed the presence of three consecutive ORFs, which potentially code for hydrophobic peptides composed of 60, 91 and 114 amino acids, respectively, and a fourth ORF of opposite polarity which could potentially encode a peptide of 59 amino acids.
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