Background: Ongoing research in the dental field has begun to focus on the use of injectable platelet-rich fibrin (I-PRF) as a regenerative tool with the potential to prompt tissue regeneration. In this regard, this systematic scoping review aimed to collect, map, and appraise the and studies regarding the role of I-PRF in or soft and hard tissue regeneration in relation to oral and maxillofacial structures.
Methods: A systematic electronic search of databases was performed from 2000 to December 2021 using a combination of keywords. All and studies, written in English and concerning the potential role of I-PRF in regenerative dentistry were considered.
Results: In total, 18 studies, 5 animal studies, 6 case reports, and 31 clinical studies have evaluated the effect of I-PRF on oral and maxillofacial soft and hard tissue regeneration. The investigated studies verified the anti-inflammatory, anti-microbial efficacy and the positive effects of I-PRF application for wound, periodontal, bone, cartilage, and pulp regeneration, as well as acceleration in tooth movement during orthodontic treatment.
Conclusions: Current literature approves the feasibility of I-PRF application as a promising regenerative adjunct to dental procedures.
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| http://dx.doi.org/10.1016/j.jdsr.2022.02.003 | DOI Listing |
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