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Effect of the strategy game Mangala on cognitive function, anxiety, depression, and fine motor skills in individuals with Alzheimer's disease: A randomized controlled trial.
Appl Neuropsychol Adult
January 2025
Denizli Elderly Care and Rehabilitation Centre, Denizli, Türkiye.
Cognitive impairment, changes in mood, and decrease in fine motor skills are some of the most common symptoms experienced by individuals with Alzheimer's Disease (AD). This study aimed to investigate the effects of the Turkish intelligence and strategy game Mangala on cognitive functions, anxiety, depression, and fine motor skills in individuals with AD. In this randomized controlled study, 37 participants were divided into Mangala Group (MG) and Control Group (CG).
View Article and Find Full Text PDFBrain serotonin, oxytocin, and their interaction: Relevance for eating disorders.
J Psychopharmacol
January 2025
Eating Disorders Continuum and Research Center, Douglas Mental Health University Institute, Montreal, QC, Canada.
Introduction: Eating disorders are characterized by maladaptive eating behaviors and preoccupations around body shape, weight, and eating. The serotonin system has been among the most widely studied neurobiological factors in relation to eating disorders. Recent research also highlighted the role of oxytocin.
View Article and Find Full Text PDFImpact of COVID-19, lockdowns and vaccination on immune responses in a HIV cohort in the Netherlands.
Front Immunol
January 2025
Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.
Introduction: During the COVID-19 pandemic, major events with immune-modulating effects at population-level included COVID-19 infection, lockdowns, and mass vaccinations campaigns. As immune responses influence many immune-mediated diseases, population scale immunological changes may have broad consequences.
Methods: We investigated the impact of lockdowns, COVID-19 infection and vaccinations on immune responses in the 2000HIV study including 1895 asymptomatic virally-suppressed people living with HIV recruited between October 2019 and October 2021.
Introduction And Objective: Dietary habits may be an essential modulator affecting diet-related cognitive decline. One hopes that their identification will allow opening the use of new approaches for the management of the prevention and treatment of patients with mild cognitive disorders and maintaining a good quality of life. The aim of the research was to characterize dietary habits in people with mild cognitive impairment (MCI).
View Article and Find Full Text PDFSleep microstructure organizes memory replay.
Nature
January 2025
Department of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA.
Recently acquired memories are reactivated in the hippocampus during sleep, an initial step for their consolidation. This process is concomitant with the hippocampal reactivation of previous memories, posing the problem of how to prevent interference between older and recent, initially labile, memory traces. Theoretical work has suggested that consolidating multiple memories while minimizing interference can be achieved by randomly interleaving their reactivation.
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