Introduction: Spontaneous pneumomediastinum is an uncommon complication of Corona Virus Disease (COVID)-19 presenting mostly in moderate to severe cases.

Materials And Methods: This is a retrospective observational imaging and hospital data-based study done on 15 confirmed patients of COVID-19 who underwent high resolution computed tomography (HRCT) thorax at the Department of Radio-Diagnosis of a tertiary medical center in the Himalayan foothills. The clinico-radiological profile of the study group was assessed and it was aimed at finding the association of pneumomediastinum with the severity of lung changes.

Results: A strong association of pneumomediastinum was observed with severe lung changes on HRCT thorax ( = 13, 87%, < 0.00001). Dyspnea was the most common presenting factor. The mortality rate is high in mechanically intubated patients of pneumomediastinum with COVID-19 (75%).

Conclusion: Pneumomediastinum is a complication of a severe COVID-19 disease spectrum. Along with severe lung parenchymal disease, systemic inflammation, systemic steroid therapy, comorbid state, and mechanical intubation, it is a part of the pool of poor prognostic factors. HRCT is essential for making a quick and comprehensive diagnosis, thereby, guiding the clinician for further management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963614PMC
http://dx.doi.org/10.4103/jfmpc.jfmpc_1346_21DOI Listing

Publication Analysis

Top Keywords

uncommon complication
8
hrct thorax
8
association pneumomediastinum
8
severe lung
8
pneumomediastinum
6
covid-19
5
pneumomediastinum radiological
4
radiological profile
4
profile associations
4
associations uncommon
4

Similar Publications

Thoracic outlet syndrome (TOS) is an uncommon condition defined by the compression of neurovascular structures within the thoracic outlet. When conservative management strategies fail to alleviate symptoms, surgical decompression becomes necessary. The purpose of this study is to evaluate and compare the efficacy and safety of regional anesthesia (RA) using spontaneous breathing in contrast to general anesthesia (GA) for patients undergoing surgical intervention for TOS.

View Article and Find Full Text PDF

Although reversible cerebral vasoconstriction syndrome (RCVS) is a rare disease, the condition may occur with COVID-19 infection. We aimed to investigate the clinical characteristics of RCVS through a systematic review of case reports and case series that reported on COVID-19-related RCVS. : A literature search was performed in PubMed (MEDLINE), SCOPUS, and Web of Science.

View Article and Find Full Text PDF

Primary Biliary Cholangitis Associated with Ulcerative Colitis: Case Series and Literature Review.

Medicina (Kaunas)

December 2024

National Clinical Research Center for Digestive Diseases, State Key Laboratory for Digestive Health, Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

: To study the coexistence of ulcerative colitis (UC) and primary biliary cholangitis (PBC). : The Beijing Friendship Hospital patient database was explored to identify patients presenting both UC and PBC from January 2015 to July 2024. By a review of the literature, the characteristics of UC patients who experienced PBC was summarized.

View Article and Find Full Text PDF

Pyogenic liver abscesses (PLAs) are serious infections in which doctors often fail in identifying the causative agent due to microbiological limitations. These limitations in detecting uncommon pathogens complicate the treatment and recovery. Molecular techniques, like massive sequencing, enable the detection of uncommon pathogens and highlight the shortcomings of traditional cultures.

View Article and Find Full Text PDF

Insights into Cancer-Associated Thrombosis Leading Towards Ischemic Stroke.

Biology (Basel)

January 2025

Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.

Stroke leads to significant disability in most patients, whereas cancer elevates the occurrence of stroke. The incidence of cancer-associated stroke (CAS) is projected to rise as a result of improvements in cancer therapies. Various forms of cancer have been demonstrated to be linked to ischemic stroke.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!