AI Article Synopsis

  • IgG4-related disease is a chronic, immune-mediated condition that can impact multiple organs, especially the pancreas and biliary system, leading to misdiagnosis due to its varied symptoms.
  • The digestive system is rarely affected, with most gastric issues arising as tumors identified via endoscopy.
  • This article highlights two unique cases involving atrophic gastritis and intestinal polyps to enhance understanding and support clinical diagnosis and treatment of IgG4-related disease.

Article Abstract

IgG4-related disease is an immune-mediated chronic, systemic, and autoinflammatory disease that can affect various organs throughout the body. The most commonly affected areas are the pancreas and biliary system. Due to the diverse clinical manifestations of the disease, it affects widely distributed organs. Thus, it is often easy to misdiagnose or miss. The digestive tract is a rarely affected system, and most IgG4-related gastric diseases manifest as tumors detected by endoscopy. This article reports two special cases with IgG4-related disease involving atrophic gastritis and intestinal polyps to provide a more empirical and theoretical basis for clinical diagnosis and treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960130PMC
http://dx.doi.org/10.3389/fimmu.2022.816830DOI Listing

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