Objective: The aim of the study was to describe focal epilepsy in patients with Laron syndrome (LS).
Methods: Data were retrieved from medical records of a single-center cohort of 75 patients with LS.
Results: We describe for the first time 4 patients with concomitant focal epilepsy and LS. Two of them experienced episodes of status epilepticus. Electroencephalogram examination in all 4 patients showed interictal epileptiform discharges in the temporal regions. Three achieved long-term seizure freedom on antiseizure medications.
Conclusion: Patients with LS may be at risk of developing focal epilepsy, which seems to be unrelated to hypoglycemic episodes in childhood.
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| http://dx.doi.org/10.1159/000524350 | DOI Listing |
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