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Anti-Scar Effects of Micropatterned Hydrogel after Glaucoma Drainage Device Implantation.
Research (Wash D C)
January 2025
Department of Ophthalmology, The Future Medicine Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, People's Republic of China.
Excessive fibrosis is the primary factor for the failure of glaucoma drainage device (GDD) implantation. Thus, strategies to suppress scar formation in GDD implantation are crucial. Although it is known that in implanted medical devices, microscale modification of the implant surface can modulate cell behavior and reduce the incidence of fibrosis, in the field of ophthalmic implants, especially the modification and effects of hydrogel micropatterns have rarely been reported.
View Article and Find Full Text PDFHighly stretchable, conductive, and self-adhesive starch-based hydrogel for high-performance flexible electronic devices.
Carbohydr Polym
March 2025
College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Key Laboratory of Organosilicon Material Technology, Hangzhou Normal University, Zhejiang Province, Hangzhou 311121, Zhejiang, People's Republic of China. Electronic address:
To achieve the green and sustainable development of environment, biocompatible hydrogels with exceptional ionic conductivity and flexibility are highly desired for intelligent and wearable sensors. However, it remains a great challenge to obtain biopolymer hydrogel-based sensors with high transparency, excellent mechanical properties, and good adhesion ability simultaneously. Herein, starch/polyacrylamide double-network hydrogel is achieved to endow the multifunctionality of traditional hydrogel sensor.
View Article and Find Full Text PDFTendon-mimicking anisotropic alginate-based double-network composite hydrogels with enhanced mechanical properties and high impact absorption.
Carbohydr Polym
March 2025
School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea; Department of MetaBioHealth, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea; Institute of Quantum Biophysics (IQB), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea. Electronic address:
Tendons are anisotropic tissues with exceptional mechanical properties, which result from their unique anisotropic structure and mechanical behavior under stress. While research has focused on replicating anisotropic structures and mechanical properties of tendons, fewer studies have examined their specific mechanical behaviors. Here, we present a simple method for creating calcium-crosslinked alginate-based double-network hydrogels that mimics tendons by exhibiting anisotropic structure, high mechanical strength and toughness, and a distinctive "toe region" when stretched.
View Article and Find Full Text PDFAnti-freezing conductive hydrogels with exceptional mechanical properties and stable sensing performance at -30 °C.
Mater Horiz
January 2025
Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin, 300350, P. R. China.
Conductive hydrogels with stable sensing performance are highly required in soft electronic devices. However, these hydrogels tend to solidify and experience structural damage at sub-zero temperatures, leading to material breakdown and device malfunction. The main challenge lies in effectively designing the micro/nano-structure to enhance mechanical properties and stable strain sensing while preventing freezing in hydrogels.
View Article and Find Full Text PDFMXene/Ag-Based Zwitterionic Double-Network Hydrogels with Enhanced Mechanical Strength and Antifouling Performances.
ACS Appl Mater Interfaces
January 2025
School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Biological fouling seriously jeopardizes the development of the marine industry. Although hydrogels, as a kind of state-of-the-art antifouling material, have received wide attention, their mechanical strength is still relatively weak, and the synergistic antifouling method is comparatively single, thus limiting the performance of hydrogels. Here, a zwitterionic sulfobetaine methacrylate (SBMA)-acrylamide (AM)/sodium alginate (SA) double-network (DN) antifouling hydrogel with superb antifouling ability and outstanding mechanical properties was prepared by grafting MXene/Ag (M/Ag) and the powerful biocide polyhexamethylene biguanide (PHMB).
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