Poly(ethylene glycol) (PEG) is the most widely used polymer to decorate inorganic nanoparticles (NPs) by the "grafting-to" method for antifouling properties. PEG also shows diverse supramolecular interactions with nanoparticle surfaces and polar molecules, suggesting that the physisorption between PEG chains and NPs cannot be ignored in the "grafting-to" process. However, the effect of physisorption of PEG to NPs on the process of chemisorption has been rarely studied. Herein, we report that unfunctionalized PEG is physically adsorbed on various NPs by polyvalent supramolecular interactions, adopting "loop-and-train-tail" conformations. We investigated the effect of molecular weight of PEG and ligands of the NPs on the conformation of PEG chains by experimental methods and simulation. It is demonstrated that the physisorption of PEG on NPs can facilitate the chemisorption in the initial stages but delays it in the later stages during the "grafting-to" process. This work provides a deeper understanding of the conformation of physisorbed PEG on NPs and the relationship between physisorption and chemisorption.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acsnano.2c01051 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bio-based sunflower carbon/polyethylene glycol shape-stabilized phase change materials for thermal energy storage.
RSC Adv
July 2024
Chongqing Copolyforce New Material Co.Ltd Chongqing 400437 China.
Article Synopsis
- - The study explores the use of sunflower biomass (stems and receptacles) mixed with polyethylene glycol to create shape-stabilized phase change materials, aiming to boost energy efficiency due to their high thermal conductivity and storage capability.
- - Sunflower stem carbon (SS-PEG) and receptacle carbon (SR-PEG) were synthesized using a vacuum impregnation method, and their structural and thermal properties were analyzed with various techniques like SEM and DSC.
- - Results indicated that SS-PEG and SR-PEG have significant melting enthalpies of 153.4 J/g and 171.5 J/g, respectively, achieving high loading rates of 81.9% and 91.5%, while also exhibiting good thermal stability with
Molecular Recognition between Carbon Dioxide and Biodegradable Hydrogel Models: A Density Functional Theory (DFT) Investigation.
Gels
June 2024
Departamento de Química y Biología, Facultad de Ciencias Básicas, Universidad del Norte, Barranquilla 080020, Colombia.
Article Synopsis
- The study investigates using density functional theory (DFT) to design biodegradable hydrogels for capturing carbon dioxide (CO) to reduce greenhouse gas emissions.
- The research identifies four hydrogel models—polyethylene glycol, polyvinylpyrrolidone, chitosan, and poly-2-hydroxymethacrylate—that show strong binding affinities to CO, with binding energies indicating physisorption.
- Findings suggest that these materials are stable at high temperatures and highlight the potential for developing new CO capture technologies, although further optimization and environmental performance assessments are needed.
Underlying Roles of Polyol Additives in Promoting CO Capture in PEI/Silica Adsorbents.
ChemSusChem
November 2024
School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Solid-supported amines having low molecular weight branched poly(ethylenimine) (PEI) physically impregnated into porous solid supports are promising adsorbents for CO capture. Co-impregnating short-chain poly(ethylene glycol) (PEG) together with PEI alters the performance of the adsorbent, delivering improved amine efficiency (AE, mol CO sorbed/mol N) and faster CO uptake rates. To uncover the physical basis for this improved gas capture performance, we probe the distribution and mobility of the polymers in the pores via small angle neutron scattering (SANS), solid-state NMR, and molecular dynamic (MD) simulation studies.
View Article and Find Full Text PDFIn vitro and in vivo Evaluation of Folic Acid Modified DOX-Loaded P-nHA Nanoparticles in Prostate Cancer Therapy.
Int J Nanomedicine
April 2023
Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
Background: Prostate cancer (PCa) ranks second in the incidence of all malignancies in male worldwide. The presence of multi-organ metastases and tumor heterogeneity often leads to unsatisfactory outcomes of conventional radiotherapy treatments. This study aimed to develop a novel folate-targeted nanohydroxyapatite (nHA) coupling to deliver adriamycin (Doxorubicin, DOX), P, and Tc simultaneously for the diagnosis and treatment of prostate-specific membrane antigen (PSMA) positive prostate cancer.
View Article and Find Full Text PDFComputational study of the effect of size and surface functionalization on Au nanoparticles on their stability to study biological descriptors.
J Mol Model
November 2022
Department of Physics, University of the Free State, Nelson Mandela Avenue, Park West, Bloemfontein, 9301, South Africa.
The effects of varying nanoparticle size; polyethylene glycol (PEG) molecule length, type, and density; and functional groups for drug delivery systems are investigated computationally. A molecular dynamics (MD) study in the framework of a Monte Carlo simulated annealing scheme is done on gold nanoparticles (Au NPs) for sizes of 2.6 nm, 3.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!