Management of Colorectal Cancer in Hereditary Syndromes.

Surg Oncol Clin N Am

Division of Colorectal Surgery, Department of Surgery, The Ohio State University Medical Center, N737B Doan Hall, 410 West 10th Avenue, Columbus, OH 43210, USA; Clinical Cancer Genetics Program, The James Comprehensive Cancer Center, Columbus, OH 43201, USA. Electronic address:

Published: April 2022

AI Article Synopsis

  • About 5% of colorectal cancers are linked to hereditary syndromes, increasing the risk of early-onset colorectal and other cancers in patients and their families.
  • Identifying and diagnosing these hereditary syndromes is essential for effective management and reducing cancer risk.
  • Surgeons need to understand the specific surgical approaches for hereditary syndromes, especially for Lynch syndrome and familial adenomatous polyposis, to optimize treatment.

Article Abstract

Approximately 5% of all colorectal cancers develop within a hereditary colorectal cancer syndrome. Patients and families with these syndromes have an increased risk of colorectal and extracolonic cancers that develop at an early age. Recognition and diagnosis of these conditions are crucial to management and risk reduction. Surgeons must be aware of the unique aspects of the timing and extent of surgery (both therapeutic and prophylactic) within these syndromes, particularly for the most common syndromes, Lynch syndrome and familial adenomatous polyposis.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.soc.2021.11.010DOI Listing

Publication Analysis

Top Keywords

colorectal cancer
8
cancers develop
8
management colorectal
4
cancer hereditary
4
syndromes
4
hereditary syndromes
4
syndromes colorectal
4
colorectal cancers
4
develop hereditary
4
hereditary colorectal
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!