Local recruitment and fueling of the cellular powerplant to support cell invasion.

Dev Cell

Department of Pathology and Laboratory Medicine, The Robert Larner M.D. College of Medicine, University of Vermont, Burlington, VT 05405, USA; University of Vermont Cancer Center, Burlington, VT 05405, USA. Electronic address:

Published: March 2022

In this issue of Developmental Cell, Garde et al. demonstrate that polarized expression of the glucose transporter FGT-1, accompanied by a localized glucose gradient and mitochondrial recruitment to the basal membrane of the anchor cell (AC), supports localized ATP generation required for basement membrane (BM) invasion in C. elegans.

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Source
http://dx.doi.org/10.1016/j.devcel.2022.03.002DOI Listing

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