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Impact of Malnutrition on Prognosis and Coronary Artery Calcification in Patients with Stable Coronary Artery Disease. | LitMetric

Impact of Malnutrition on Prognosis and Coronary Artery Calcification in Patients with Stable Coronary Artery Disease.

Curr Probl Cardiol

Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Published: August 2023

AI Article Synopsis

  • - Nutritional status significantly impacts the prognosis of cardiovascular diseases, with malnutrition linked to higher rates of all-cause death (22% vs 5%) and major cardiovascular and cerebrovascular events (MACCE) (24% vs 6%) in patients undergoing treatment for coronary artery disease.
  • - In a study of 500 stable coronary artery disease patients, malnutrition was found to correlate significantly with increased risks of all-cause death and MACCE, highlighting its role as an independent risk factor.
  • - The research showed that malnourished patients had a higher prevalence of moderate/severe coronary calcification (64%) compared to non-malnourished patients (33%), indicating a link between nutritional status and the severity of

Article Abstract

Nutritional status is an important factor affecting prognosis of cardiovascular diseases. We compared major cardiovascular and cerebrovascular events (MACCE) between the malnutrition (geriatric nutritional risk index <92) and non-malnutrition (geriatric nutritional risk index ≥92) groups in 500 stable coronary artery disease patients undergoing percutaneous coronary intervention and evaluated coronary calcification by intravascular ultrasound. Incidences of all-cause death and MACCE differed between the malnutrition and non-malnutrition groups (22% vs 5%, P < 0.001 and 24% vs 6%, P < 0.001). In multivariate Cox proportional hazards regression, malnutrition significantly correlated with all-cause death (P = 0.006) and MACCE (P = 0.010). The proportion of moderate/severe calcification differed between the malnutrition (64%) and non-malnutrition groups (33%, P < 0.001). Multivariate logistic analysis identified age (P < 0.001), malnutrition (P = 0.048), and hemodialysis (P < 0.001) as significantly related to moderate/severe calcification. Malnutrition was an independent risk factor for all-cause death and MACCE in coronary artery disease patients after percutaneous coronary intervention and was associated with moderately/severely calcified lesions.

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Source
http://dx.doi.org/10.1016/j.cpcardiol.2022.101185DOI Listing

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