The most common neurological symptom of spontaneous intracranial hypotension (SIH) is abducens nerve paresis, and the precise pathophysiology is unclear. The accepted explanation is traction on the cranial nerves caused by the downward displacement of the cranial content. We herein report magnetic resonance imaging of SIH that can explain the mechanism underlying abducens nerve paresis. The cavernous sinuses were particularly thickened compared with the surrounding dura. This phenomenon can be explained by venous swelling, which can occur after leakage of cerebrospinal fluid in a closed cavity. This swelling pushes the abducens nerve up, which then causes abducens nerve paresis.
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http://dx.doi.org/10.2169/internalmedicine.8488-21 | DOI Listing |
J Rhinol
March 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.
Isolated sphenoid fungal sinusitis (ISFS) is a rare condition characterized by fungal infection of the sphenoid sinus. It often presents with non-specific symptoms, which can lead to misdiagnosis. This study presents two unique cases of ISFS with mucocele that were initially misdiagnosed as chordoma based on preoperative radiographic findings.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Rationale: Hypertrophic pachymeningitis (HP) is a rare and complex condition marked by inflammation and thickening of the dura mater. It can occur either on its own or as a result of various underlying medical issues. This type of granulomatous meningitis is extremely rare and poorly understood, making diagnosis and treatment particularly challenging.
View Article and Find Full Text PDFCureus
November 2024
Otolaryngology, Royal Surrey County Hospital, Guildford, GBR.
A 66-year-old woman with no prior medical history presented to the emergency department with diplopia and parosmia. The neurological examination identified an isolated left abducens nerve (CN VI) palsy. A head CT scan, followed by a brain MRI, showed a large, locally advanced tumour in the left sphenoid sinus with extensive skull base involvement and perineural extension into the left orbit.
View Article and Find Full Text PDFNMC Case Rep J
November 2024
Department of Neurosurgery, Yokohama City University, School of Medicine, Yokohama, Kanagawa, Japan.
Isolated abducens nerve palsy (IANP), caused by secondary communicating hydrocephalus, has been rarely documented; in addition, its mechanism and appropriate treatment are not understood well. This study presents a case of bilateral IANP with hydrocephalus in a 62-year-old man who was successfully treated with cerebrospinal fluid (CSF) diversion to correct an enlarged retroclival space during the follow-up of recurrent brain tumor in the right parieto-occipital lobe. The patient was treated with three resections, temozolomide, and irradiation before developing IANP.
View Article and Find Full Text PDFSurg Neurol Int
November 2024
Department of Neurosurgery, Ibn Sina Hospital, Al-Sabah Medical Area, Kuwait City, Kuwait.
Background: Isolated sphenoid sinus fungal mucoceles are extremely rare and potentially associated with visual disturbances, cranial nerve (CN) deficits, or pituitary dysfunction. Their initial symptoms are often absent or nonspecific, and routine examination offers little information, resulting in diagnostic and therapeutic delays. A high index of suspicion and a thorough understanding of their clinical presentation, neuroradiological features, microbiological implications, and complication profile are crucial for early diagnosis and prompt management.
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