A novel 1-step anionic surfactant disinfectant was effective against isolates from the 4 major phylogenetic clades as well as methicillin-resistant (MRSA) and the enveloped virus bacteriophage Phi6. This anionic surfactant disinfectant may be a useful addition to the disinfectant products available for use against .
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http://dx.doi.org/10.1017/ice.2022.73 | DOI Listing |
Liver Cancer
October 2024
Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
Introduction: Patients with hepatitis virus-related hepatocellular carcinoma (viral HCC) are decreasing as hepatitis control improves, but those with non-viral-related HCC (non-viral HCC) are increasing in Japan. No established surveillance system exists for patients with non-viral HCC, so they are often diagnosed at an advanced stage. To address this, we performed this study.
View Article and Find Full Text PDFClin Pharmacol Ther
February 2025
Genentech, Inc., South San Francisco, California, USA.
Mosunetuzumab, a T-cell engaging bispecific antibody targeting CD20xCD3, is approved for treating relapsed/refractory follicular lymphoma. This research supports the approved intravenous clinical dose regimen, summarizing the exposure-response relationships for clinical safety and efficacy. A population pharmacokinetic model and E logistic regression exposure-response models for safety and efficacy were developed using data from 439 patients with relapsed/refractory non-Hodgkin lymphoma and 159 patients with relapsed/refractory follicular lymphoma, respectively, from a Phase I/II study (NCT02500407).
View Article and Find Full Text PDFCirculation
September 2024
Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center/New York-Presbyterian Hospital, NY (A.L., G.M., E.D., T.M., M.M., A.J.E., D.K., S.H., Q.L., V.A., M. Lebehn, M. Leon, R.H., P.E., T.J.P.).
J Health Econ Outcomes Res
May 2024
Pain Unit Santa Maria Maddalena Hospital, Occhiobello, Italy.
Spinal cord stimulation (SCS) is a treatment for chronic intractable pain powered by an implantable pulse generator that may be rechargeable or not rechargeable (NR). It is performed in 2 stages (a trialing phase followed by permanent device implantation) and necessitates 2 hospitalizations, which may increase infection risk. This analysis explores the cost impact of improvements in battery longevity and the adoption of 1-step (direct-to-implant [DTI]) SCS implantation.
View Article and Find Full Text PDFNanomaterials (Basel)
April 2024
Quantum Device Physics Laboratory, Universidade Estadual de Campinas (Unicamp), Instituto de Física Gleb Wataghin (IFGW), Campinas 13083-859, SP, Brazil.
This paper explores methods to enhance the reproducibility of Josephson junctions, which are crucial elements in superconducting quantum technologies, when employing the Dolan technique in 30 kV e-beam processes. The study explores the influence of dose distribution along the bridge area on reproducibility, addressing challenges related to fabrication sensitivity. Experimental methods include e-beam lithography, with electron trajectory simulations shedding light on the behavior of backscattered electrons.
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