AI Article Synopsis
- - Researchers studied hiccups as a symptom of lateral medullary infarction (LMI) to understand which part of the brain is involved.
- - The study analyzed 31 LMI patients from 2008 to 2018, finding that 11 of them (35.5%) experienced hiccups, and the brain imaging revealed lesions in specific areas.
- - Conclusions suggest that injury to the dorsolateral region of the middle medulla may be linked to the occurrence of hiccups in these patients.
Article Abstract
Background: Hiccups is a known presentation of lateral medullary infarction. However, the region in the medulla associated with this finding is not clearly known. In this study, we aimed to study the neural correlates of hiccups in patients with lateral medullary infarction (LMI).
Methods: This retrospective study included all patients who presented with lateral medullary infarction between January 2008 and May 2018. Patients with hiccups following LMI were identified as cases and those with no hiccups but who had LMI were taken as controls. The magnetic resonance imaging of the brain was done viewed and individual lesions were mapped manually to the template brain. Voxel-based lesion-symptom mapping employing nonparametric permutation testing was performed using MRIcron.
Results: There were a total of 31 patients with LMI who presented to the hospital during the study period. There were 11 (35.5%) patients with hiccups. Using the voxel-based lesion-symptom mapping analysis, the dorso-lateral region of the middle medulla showed significant association with hiccups.
Conclusion: In patients with LMI, we postulate that damage to the dorsolateral aspect on the middle medulla could result in hiccups.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948327 | PMC |
| http://dx.doi.org/10.1177/09727531211023753 | DOI Listing |
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