AI Article Synopsis
- - The study assessed the prevalence of antimicrobial resistance in samples from a slaughterhouse, finding that 31% tested positive for specific resistant strains, with more positive samples before chilling than after.
- - Multidrug resistance was prevalent, affecting 72% of one type of isolate and 69% of another, with significant genetic markers identified in both strains, including specific efflux pump genes and mutations in critical rRNA genes.
- - The findings aim to enhance understanding of antimicrobial-resistant organisms in food animals in Argentina and to support the development of a monitoring system for such resistance.
Article Abstract
The aim of this study was to evaluate the percentage of ( and ) from samples collected at the slaughterhouse to describe the prevalence of resistance to selected antimicrobials, and to characterize the genetic determinants. In total, from 333 samples analyzed, 31% were positive for More positive samples were detected before the chiller (46%) than after the chiller (16%). (59%) was more prevalent than (41%). Antimicrobial resistance differences between and were found (p < 0.001). Multidrug resistance was found in 72% of isolates and 69% of isolates (p < 0.001). Most isolates (57%) had the three genes of the efflux pump. The gene and resistance-associated point mutations within both the and 23S rRNA genes were detected in 100% of isolates. On the other hand, only had more prevalence of the gene than (p < 0.001), and most of the isolates (70-80%) had the and point mutation. These results could contribute to knowledge about the status of thermotolerant resistant to antimicrobials isolated from food animals in Argentina and to develop an antimicrobial resistance surveillance system.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943338 | PMC |
| http://dx.doi.org/10.1016/j.crfs.2022.03.005 | DOI Listing |
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