The widely used ice chamber-based cold storage for the transportation and storage of vaccines has several disadvantages, including uncontrolled overall temperature, water accumulation, and frequent ice pack renewal. Therefore, in this work, we numerically studied a novel vaccine storage system by coupling magnetic refrigeration and ice packs developed by conserving the advantages of an ice-based system. A two-dimensional numerical model is developed to analyze the magnetohydrodynamic natural convection in the storage chamber. Gadolinium of 0.08 kg is used to produce a cooling power of 31.514 W and a coefficient of performance of 1.3. With the constant heat leaked of 0.828 W into the system with dimensions of (0.1 × 0.1) m, the average life of the ice pack of 0.75 kg is 1.03 h. By introducing the magnetocaloric effect, the life of the same ice pack can be infinite with no load. The dynamic mode decomposition analysis reveals that the most dominant fluid interaction occurs between the cooled gadolinium plate and the adjacent fluid, resulting in efficient cooling of the air chamber. The developed vaccine chamber design will significantly improve the existing ice pack system with a nominal increase in cost and system weight.
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http://dx.doi.org/10.1063/5.0077701 | DOI Listing |
PLoS One
December 2024
Department of Ecology and Evolution, Stony Brook University, Stony Brook, New York, United States of America.
We explore the habitat use of Antarctic pack-ice seals by analyzing their occupancy patterns on pack-ice floes, employing a novel combination of segmented generalized linear regression and fine-scale (∼ 50 cm pixel resolution) sea ice feature extraction in satellite imagery. Our analysis of environmental factors identified ice floe size, fine-scale sea ice concentration and nearby marine topography as significantly correlated with seal haul out abundance. Further analysis between seal abundance and ice floe size identified pronounced shifts in the relationship between the number of seals hauled out and floe size, with a positive relationship up to approximately 50 m2 that diminishes for larger floe sizes and largely plateaus after 500 m2.
View Article and Find Full Text PDFReprod Health
December 2024
UNDP‑UNFPA‑UNICEF‑WHO‑World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, 20 Avenue Appia, 1211, Geneva, Switzerland.
Background: The use of medical abortion using either a combination of mifepristone and misoprostol, or misoprostol alone has contributed to increased safety and decreased mortality and morbidity. The availability of quality medical abortion medicines is an essential component in the provision of quality abortion care. Understanding the factors that influence the availability of medical abortion medicines is important to help in-country policymakers, program planners, and providers improve availability and use of medical abortion.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Centro Hospitalar Universitário de Santo António, Porto, PRT.
Ptosis, or eyelid drooping, can be an early indicator of various neurological and muscular disorders, underscoring the need for accurate diagnosis to ensure proper management. Myasthenia gravis (MG), a neuromuscular disorder, may initially present with isolated ocular symptoms, often resulting in diagnostic delays. This report details the case of a 72-year-old male who presented to the emergency department with a two-week history of progressive unilateral ptosis.
View Article and Find Full Text PDFBiomedicines
October 2024
Monash Biomedicine Discovery Institute, Department of Physiology, Monash University, Melbourne, VIC 3800, Australia.
Background: Caloric vestibular stimulation (CVS) is a well-established neurological diagnostic technique that also induces many phenomenological modulations, including reductions in phantom limb pain (PLP), spinal cord injury pain (SCIP), and central post-stroke pain.
Objective: We aimed to assess in a variety of persistent pain (PP) conditions (i) short-term pain modulation by CVS relative to a forehead ice pack cold-arousal control procedure and (ii) the duration and repeatability of CVS modulations. The tolerability of CVS was also assessed and has been reported separately.
Acta Histochem
December 2024
Laboratory of Histopathology and Cytopathology, Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Japan. Electronic address:
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