Background: is an environmental black fungus that rarely causes respiratory infections, yet its pathophysiological features and treatment regimens have not been established.
Case Series: Two cases of exacerbations of chronic bronchitis and sinusitis due to infection in Japan are presented. Both patients were women, and non-tuberculous (NTM) infection was suspected based on chest radiological findings, but was detected from bronchial lavage fluid and nasal mucus, respectively. Both cases were successfully treated by antifungal agents such as liposomal amphotericin B, voriconazole, and itraconazole, but clarithromycin, rifampicin, ethambutol, and sitafloxacin for NTM were not effective.
Conclusion: can become a respiratory pathogen, especially in patients with chronic sinobronchial syndrome.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948093 | PMC |
http://dx.doi.org/10.2147/IDR.S359646 | DOI Listing |
Respir Investig
January 2025
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawazumi Mizuho-machi, Nagoya, 467-860, Japan.
Respir Investig
November 2024
Kanazawa Kasuga Clinic, Motogikumachi 20-1, Kanazawa, Ishikawa, 920-0036, Japan. Electronic address:
We report temporal changes in sputum rheological parameters after SARS-CoV-2 infection in two patients with chronic cough (71-year-old, male, sinobronchial syndrome; 80-year-old, female, cough variant asthma). Both patients complained of decreased cough-related quality of life and increased phlegm stickiness after infection. In parallel, their sputum showed decreases in linear viscoelastic region (LVR) parameters, such as viscoelastic modulus (G), elastic modulus (G'), and viscous modulus (G″), and increased tack (tan δ/G'; tan δ = G″/G') compared to pre-infection levels.
View Article and Find Full Text PDFRespir Investig
May 2024
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawazumi Mizuho-machi, Nagoya, 467-860, Japan.
Respir Investig
January 2024
Respiratory Disease Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association, Tokyo, Japan.
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired motile cilia function, particularly in the upper and lower airways. To date, more than 50 causative genes related to the movement, development, and maintenance of cilia have been identified. PCD mostly follows an autosomal recessive inheritance pattern, in which PCD symptoms manifest only in the presence of pathogenic variants in both alleles.
View Article and Find Full Text PDFCan Respir J
October 2022
Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Objective: This study aimed to clarify the characteristics of cough-reflex sensitivity and airway inflammation in patients with sinobronchial syndrome (SBS).
Methods: 39 patients with SBS, 53 patients with upper airway cough syndrome (UACS) induced by rhinitis, 33 patients with chronic sinusitis without cough, and 39 healthy controls (HCs) were enrolled between January 2013 and December 2018. All participants underwent a capsaicin cough-sensitivity test and cytology of induced sputum.
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