NMR spectroscopy of lipidic cubic phases.

Biophys Rev

Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3052 Australia.

Published: February 2022

Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921435PMC
http://dx.doi.org/10.1007/s12551-021-00900-yDOI Listing

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