[The correlation between blood glucose level and muscle mass, strength and function in an elderly population].

To explore the correlation between blood glucose levels and the three factors of sarcopenia (muscle mass, strength and function) in older Chinese community dwellers. This is a retrospective study conducted by collecting the data of patients in Jiangsu Huaqiao Road Community Health Service Center from 2018 to 2019. Two hundred and fifty people aged 60 years or elder were selected. Among them, 101 were men and 149 were women. According to the American Diabetes Association diagnostic criteria for diabetes mellitus in 2018, they were divided into normal glucose tolerance (NGT) group, pre-diabetes group and diabetes group. The patients were assessed for sarcopenia as well. Compared with those in the NGT group, muscle mass and upper limb muscle strength did not change in the diabetic group, but lower limb muscle strength and body function [walking speed, balance, short physical performance battery (SPPB)] decreased significantly in the diabetic group. Pearson correlation analyses showed that fasting plasma glucose(FPG) was negatively correlated with walking speed (=-0.248, =0.001), three-pose balance (=-0.166, =0.013) and SSPB (=-0.213, =0.001). Glycosylated hemoglobin A1c(HbA1c) was positively correlated with sitting and standing time (=0.205, =0.002), and negatively correlated with three-pose balance (=-0.186, =0.006) and SSPB (=-0.154, =0.024). Multiple regression analyses showed that FPG was negatively associated with walking speed (β=-0.125, =0.005) and SPPB (β=-0.034, =0.012), and that HbA1c was positively associated with sitting and standing time (β= 0.218, =0.006) and negatively associated with three-pose balance (β=-0.143, =0.012), and SPPB (β=-0.117, =0.036). There is no significant correlation between blood glucose levels and muscle mass in the elderly; however, FPG is closely correlated with gait speed, and HbA1c is closely correlated with muscle strength of lower limbs and balance ability in the elderly.