A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Improving sensitivity and connectivity of retinal vessel segmentation via error discrimination network. | LitMetric

Improving sensitivity and connectivity of retinal vessel segmentation via error discrimination network.

Med Phys

Guangdong Provincial Key Laboratory of Medical Image Processing, Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China.

Published: July 2022

Purpose: Automated retinal vessel segmentation is crucial to the early diagnosis and treatment of ophthalmological diseases. Many deep-learning-based methods have shown exceptional success in this task. However, current approaches are still inadequate in challenging vessels (e.g., thin vessels) and rarely focus on the connectivity of vessel segmentation.

Methods: We propose using an error discrimination network (D) to distinguish whether the vessel pixel predictions of the segmentation network (S) are correct, and S is trained to obtain fewer error predictions of D. Our method is similar to, but not the same as, the generative adversarial network. Three types of vessel samples and corresponding error masks are used to train D, as follows: (1) vessel ground truth; (2) vessel segmented by S; (3) artificial thin vessel error samples that further improve the sensitivity of D to wrong small vessels. As an auxiliary loss function of S, D strengthens the supervision of difficult vessels. Optionally, we can use the errors predicted by D to correct the segmentation result of S.

Results: Compared with state-of-the-art methods, our method achieves the highest scores in sensitivity (86.19%, 86.26%, and 86.53%) and G-Mean (91.94%, 91.30%, and 92.76%) on three public datasets, namely, STARE, DRIVE, and HRF. Our method also maintains a competitive level in other metrics. On the STARE dataset, the F1-score and area under the receiver operating characteristic curve (AUC) of our method rank second and first, respectively, reaching 84.51% and 98.97%. The top scores of the three topology-relevant metrics (Conn, Inf, and Cor) demonstrate that the vessels extracted by our method have excellent connectivity. We also validate the effectiveness of error discrimination supervision and artificial error sample training through ablation experiments.

Conclusions: The proposed method provides an accurate and robust solution for difficult vessel segmentation.

Download full-text PDF

Source
http://dx.doi.org/10.1002/mp.15627DOI Listing

Publication Analysis

Top Keywords

vessel segmentation
12
error discrimination
12
vessel
9
retinal vessel
8
discrimination network
8
error
7
method
6
segmentation
5
vessels
5
improving sensitivity
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!