The development and clinical application of microscopic endoscopy for in vivo optical biopsies: Endocytoscopy and confocal laser endomicroscopy.

Photodiagnosis Photodyn Ther

The Biosensor National Special Laboratory, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, People's Republic of China. Electronic address:

Published: June 2022

AI Article Synopsis

  • - Endoscopies play a key role in diagnosing diseases across various medical fields, with biopsies being the standard method for accurate diagnosis.
  • - Traditional random biopsy techniques can lead to sampling errors and delays in diagnosis.
  • - New technologies like endocytoscopy and confocal laser endomicroscopy are being developed for real-time imaging of lesions, offering potential improvements with some limitations still to address.

Article Abstract

Endoscopies are crucial for detecting and diagnosing diseases in gastroenterology, pulmonology, urology, and other fields. To accurately diagnose diseases, sample biopsies are indispensable and are currently considered the gold standard. However, random 4-quadrant biopsies have sampling errors and time delays. To provide intraoperative real-time microscopic images of suspicious lesions, microscopic endoscopy for in vivo optical biopsy has been developed, including endocytoscopy and confocal laser endomicroscopy. This article reviews recent advances in technology and clinical applications, as well as their shortcomings and future directions.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2022.102826DOI Listing

Publication Analysis

Top Keywords

microscopic endoscopy
8
endoscopy vivo
8
vivo optical
8
endocytoscopy confocal
8
confocal laser
8
laser endomicroscopy
8
development clinical
4
clinical application
4
application microscopic
4
optical biopsies
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!