Ginger extracts have anti-inflammatory, antioxidant, antitumor, and antibacterial activities mainly due to gingerols and shogaols. Extract composition and functionality can be affected by drying and extraction processes. Alternative methods to obtain ginger extracts based on high contents of gingerols and shogaols have been reported. However, there were no studies that present a broad overview of how these methods affect the composition and functionalities of ginger extracts. Based on literature data from 2011 to 2022, this review shows how drying, extraction, and complementary processes (i.e., enzymatic, acidic, and carbonic maceration) affect the composition and bioactivity of the ginger extract. Lower temperature processes, including freeze-drying, cold ultrasound-, or enzyme-assisted extraction, lead to extracts richer in phenolics, gingerols, and antioxidant activity. On the other hand, acidic solvents or "hot" processes including microwave-drying, pressurized liquid, and microwave-assisted extraction can favor higher shogaols concentrations, which have higher antitumor, anti-inflammatory, and antimicrobial activities than the gingerols precursors. Thus, in this review, we analyzed and discussed the relation between ginger processing and their bioactive compounds, focusing especially on gingerols and shogaols, as well as the main processes that increase the content of 6-shogaol without compromising other phenolic compounds to produce highly functional extracts for future applications in the food packaging sector.
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http://dx.doi.org/10.1016/j.foodres.2022.111043 | DOI Listing |
Pharmaceuticals (Basel)
November 2024
Department of Biochemistry, King George Medical University, Lucknow 226003, India.
PLoS One
November 2024
Pharmacology Unit, Faculty of Medicine and Defence Health, National Defence University of Malaysia, Kuala Lumpur, Malaysia.
Research (Wash D C)
November 2024
State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, China.
Dietary factors play a crucial role in irritable bowel syndrome (IBS) pathogenesis. Therefore, the dietary contraindications for patients with IBS require further supplementation. Recent investigations have revealed that ginger consumption may pose a risk of aggravating the symptoms and incidence of IBS; however, the specific mechanism remains unknown.
View Article and Find Full Text PDFFood Chem
February 2025
Department of Pharmaceutical Engineering, Faculty of Technology Novi Sad, University of Novi Sad, Boulevard Cara Lazara 1, 21000 Novi Sad, Serbia. Electronic address:
The usage of ginger (Zingiber officinale) has increased in recent years due to its positive effect on human health affiliated with its richness in gingerols and shogaols. This study optimized the Ultrasound-assisted extraction (UAE) for better phenolic compounds isolation from ginger herbal dust (GHD), a filter tea industry by-product. The extraction was performed using raw and defatted GHD-previously processed by Supercritical fluid extraction - CO.
View Article and Find Full Text PDFAppl Environ Microbiol
October 2024
Biodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Unlabelled: 6-Gingerol is a major phenolic compound within ginger (), often used in healthcare; however, its lower bioavailability is partly due to its poor solubility. Four bacterial glycosyltransferases (GTs) were tested to glycosylate 6-gingerol into soluble gingerol glucosides. UGT489 was a suitable GT to biotransform 6-gingerol into five significant products, which could be identified via nucleic magnetic resonance and mass spectrometry as 6-gingerol-4',5---diglucoside (), 6-gingerol-4'---glucoside (), 6-gingerol-5---glucoside (), 6-shogaol-4'---glucoside (), and 6-shogaol ().
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