The wild grass Brachypodium distachyon as a developmental model system.

Curr Top Dev Biol

Department of Plant Sciences, University of California, Davis, CA, United States; Howard Hughes Medical Institute, Chevy Chase, MD, United States. Electronic address:

Published: April 2022

AI Article Synopsis

  • Advances in sequencing and gene editing allow researchers to use new model organisms to study unique biological phenomena, like how different species respond to climate change.* -
  • The authors aim to highlight Brachypodium distachyon as a valuable grass model system for developmental biology, outlining the tools and discoveries related to it.* -
  • The review will also include personal experiences with B. distachyon and provide guidance on important considerations when working with new model systems.*

Article Abstract

The arrival of cheap and high-throughput sequencing paired with efficient gene editing technologies allows us to use non-traditional model systems and mechanistically approach biological phenomena beyond what was conceivable just a decade ago. Venturing into different model systems enables us to explore for example clade-specific environmental responses to changing climates or the genetics and development of clade-specific organs, tissues and cell types. We-both early career researchers working with the wild grass model Brachypodium distachyon-want to use this review to (1) highlight why we think B. distachyon is a fantastic grass developmental model system, (2) summarize the tools and resources that have enabled discoveries made in B. distachyon, and (3) discuss a handful of developmental biology vignettes made possible by using B. distachyon as a model system. Finally, we want to conclude by (4) relating our personal stories with this emerging model system and (5) share what we think is important to consider before starting work with an emerging model system.

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Source
http://dx.doi.org/10.1016/bs.ctdb.2021.12.012DOI Listing

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