Modified vaccinia Ankara (MVA) is a promising vaccine vector due to its highly attenuated phenotype and good immunogenicity. However, obtaining a new recombinant MVA remains a tedious and laborious procedure involving many rounds of plaque purification. Recombinant MVA generation can be greatly improved and facilitated by different selection techniques. Here, we describe a comparison between techniques based on K1L, F13L and D4R genes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954814 | PMC |
| http://dx.doi.org/10.3390/v14030528 | DOI Listing |
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